Nutrient intake in the bovine during early and mid-gestation causes sex-specific changes in progeny plasma IGF-I, liveweight, height and carcass traits

Micke, G. C., Sullivan, T. M., Gatford, K. L., Owens, J. A. and Perry, V. E. A. (2010) Nutrient intake in the bovine during early and mid-gestation causes sex-specific changes in progeny plasma IGF-I, liveweight, height and carcass traits. Animal Reproduction Science, 121 3-4: 208-217. doi:10.1016/j.anireprosci.2010.05.017


Author Micke, G. C.
Sullivan, T. M.
Gatford, K. L.
Owens, J. A.
Perry, V. E. A.
Title Nutrient intake in the bovine during early and mid-gestation causes sex-specific changes in progeny plasma IGF-I, liveweight, height and carcass traits
Journal name Animal Reproduction Science   Check publisher's open access policy
ISSN 0378-4320
1873-2232
Publication date 2010-09
Sub-type Article (original research)
DOI 10.1016/j.anireprosci.2010.05.017
Volume 121
Issue 3-4
Start page 208
End page 217
Total pages 10
Editor A. C. O. Evans
G. N. Hinch
J. E. Kinder
Place of publication Amsterdam, Netherlands
Publisher Elsevier
Collection year 2011
Language eng
Formatted abstract
Fetal and postnatal growth are mediated by insulin-like growth factors (IGFs) and their binding proteins (IGFBPs). Maternal nutrient intake during gestation can program the postnatal IGF-axis. This may have significant economic implications for beef cattle production. Weinvestigated the effect of high (H= 240%) and low (L = 70%) levels of recommended daily crude protein (CP) intake for heifers during the first and second trimesters of gestation in a two-by-two factorial design on progeny (n = 68) plasma IGF-I, IGF-II, total IGFBP (tIGFBP), postnatal growth and carcass traits. Calves were heavier at birth following high CP diets during the second trimester (P = 0.03) and this persisted to 29 d. Plasma IGF-I concentrations of males were greater for HL compared to LL (P < 0.01) and HH (P > 0.04) from 29 to 657 d, and for LH compared to LL from 29 until 379 d (P = 0.02). Exposure to low CP diets during the first trimester resulted in heavier males from 191 d onwards (P = 0.04) but a tendency for lighter females from 552 d onwards (P = 0.07) that had lighter carcass weights (P = 0.04). Longissimus dorsi cross-sectional area of all carcasses was greater following exposure to low CP diets during the second trimester (P = 0.04). Heifer nutrient intake during the first and second trimesters causes persistent and sex-specific programming of progeny plasma IGF-I, postnatal liveweight and carcass weight. Refining heifer nutritional programs during early gestation may optimize production objectives in progeny.
© 2010 Elsevier B.V. All rights reserved.
Keyword Cattle
Fetal programming
IGF
Maternal nutrition
Metabolites
Postnatal growth
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Veterinary Science Publications
 
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Created: Fri, 11 Feb 2011, 11:29:51 EST by Annette Winter on behalf of School of Veterinary Science