Organosilica particles for DNA screening applications

Corrie, Simon, Lawrie, Gwen, Battersby, Bronwyn and Trau, Matt (2006). Organosilica particles for DNA screening applications. In: 2006 International Conference on Nanoscience and Nanotechnology. Proceedings. ICONN 2006: International Conference On Nanoscience and Nanotechnology, Brisbane, QLD, Australia, (190-193). 3-7 July, 2006. doi:10.1109/ICONN.2006.340599


Author Corrie, Simon
Lawrie, Gwen
Battersby, Bronwyn
Trau, Matt
Title of paper Organosilica particles for DNA screening applications
Conference name ICONN 2006: International Conference On Nanoscience and Nanotechnology
Conference location Brisbane, QLD, Australia
Conference dates 3-7 July, 2006
Proceedings title 2006 International Conference on Nanoscience and Nanotechnology. Proceedings
Journal name International Conference on Nanoscience and Nanotechnology. Proceedings
Place of Publication Piscataway, NJ, USA
Publisher IEEE
Publication Year 2006
Sub-type Fully published paper
DOI 10.1109/ICONN.2006.340599
Open Access Status
ISBN 1424404533
9781424404537
9781424404520
ISSN 2150-3591
2150-3605
Volume 1
Start page 190
End page 193
Total pages 4
Language eng
Formatted Abstract/Summary
Particle-based libraries for chemical screening are of interest for robust biochemical assays and molecular diagnostic applications. Silica particles are chemically stable and possess two separate chemical modification pathways that facilitate the attachment of fluorescent dyes for encoding purposes and specific oligonucleotides for hybridization assays. Characterization of surface modifications of the particles are presented and quantitation of oligonucleotide probes on the particle surface is described. The application of the particles in biological screening experiments is presented by means of a single base mismatch detection assay.
Keyword 3-Mercaptopropyl trimethoxysilane
DNA hybridization
Flow cytometry
Particles
Surface modifications
Q-Index Code E1
Q-Index Status Provisional Code
Institutional Status UQ
Additional Notes Online pagination: 250-253.

Article # 4143379. Presented during Symposium B: "Bio-Nanotechnology, Nano-Medicine and Nanobionics" as "Nanostructured organosilica particles for DNA screening applications".

 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 0 times in Thomson Reuters Web of Science Article
Scopus Citation Count Cited 0 times in Scopus Article
Google Scholar Search Google Scholar
Created: Thu, 10 Feb 2011, 16:58:10 EST by Mr Simon Corrie on behalf of Aust Institute for Bioengineering & Nanotechnology