Adaptive climatic molecular evolution in wild barley at the Isa defense locus

Cronin, James K., Bundock, Peter C., Henry, Robert J. and Nevo, Eviatar (2007) Adaptive climatic molecular evolution in wild barley at the Isa defense locus. Proceedings of the National Academy of Sciences of the United States of America, 104 8: 2773-2778.


Author Cronin, James K.
Bundock, Peter C.
Henry, Robert J.
Nevo, Eviatar
Title Adaptive climatic molecular evolution in wild barley at the Isa defense locus
Journal name Proceedings of the National Academy of Sciences of the United States of America  (ERA 2012 Listed)    (ERA 2010 Rank A*)   Check publisher's open access policy
Publication date 2007-02
Sub-type Article
DOI 10.1073/pnas.0611226104
Volume number 104
Issue number 8
ISSN 0027-8424
1091-6490
Start page 2773
End page 2778
Total pages 6
Place of publication Washington, DC United States
Publisher National Academy of Sciences
Language eng
Formatted abstract Wild barley (Hordeum spontaneum) represents a significant genetic resource for crop improvement in barley (Hordeum vulgare) and for the study of the evolution and domestication of plant populations. The Isa gene from barley has a putative role in plant defense. This gene encodes a bifunctional α-amylase/subtilisin inhibitor that inhibits the bacterial serine protease subtilisin, fungal xylanase, and the plant's own α-amylase. The inhibition of plant α-amylases suggests this protein may also be important for grain quality from a human perspective. We identified 16 SNPs in the coding region of the Isa locus of 178 wild barley accessions from eight climatically divergent sites across Israel. The pattern of SNPs suggested a large number of recombination events within this gene, indicating that the low-outcrossing rate of wild barley is not a barrier to recombinant haplotypes becoming established in the population. Seven amino acid substitutions were present in the coding region. Genetic diversity for each population was calculated by using Nei's diversity index, and a Spearman rank correlation was carried out to test the association between gene diversity and 16 ecogeographical factors. Highly significant correlations were found between diversity at the Isa locus and key water variables, evaporation, rainfall, humidity, and latitude. The pattern of association suggests selective sweeps in the wetter climates, with resulting low diversity and weaker selection or diversifying selection in the dryer climates resulting in much higher diversity. © 2007 by The National Academy of Sciences of the USA.
Keyword Climatic selection
Crop improvement
Hordeum spontaneum
Isa molecular
Polymorphism
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article
Collections: Queensland Alliance for Agriculture and Food Innovation
ERA 2012 Admin Only
 
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