Pleiotropy, apparent stabilizing selection and uncovering fitness optima

McGuigan, Katrina, Rowe, Locke and Blows, Mark W. (2011) Pleiotropy, apparent stabilizing selection and uncovering fitness optima. Trends In Ecology & Evolution, 26 1: 22-29. doi:10.1016/j.tree.2010.10.008

Author McGuigan, Katrina
Rowe, Locke
Blows, Mark W.
Title Pleiotropy, apparent stabilizing selection and uncovering fitness optima
Journal name Trends In Ecology & Evolution   Check publisher's open access policy
ISSN 1528-2619
Publication date 2011-01
Year available 2010
Sub-type Article (original research)
DOI 10.1016/j.tree.2010.10.008
Volume 26
Issue 1
Start page 22
End page 29
Total pages 8
Place of publication Chicago Ill, U.S.A.
Publisher Dept. of Ecology and Evolution, University of Chicago
Collection year 2011
Language eng
Abstract Evolutionary theory has emphasized that the evolution of single traits cannot be understood in isolation when pleiotropy is present. Widespread pleiotropy causes the appearance of stabilizing selection on metric traits owing to joint effects with fitness, and results in the genetic variation being concentrated in relatively few combinations of the measured traits. In this review, we show how trait combinations with high levels of genetic variation can be used to uncover fitness optima that are defined by apparent stabilizing selection. Defining fitness optima in this way could provide one avenue by which researchers can overcome the problem posed by measuring the myriad of traits that must influence fitness, or by measuring total fitness itself. © 2010 Elsevier Ltd.
Keyword Evolutionary theory
Genetic variation
Life history trait
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Available online 20 November, 2010.

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Biological Sciences Publications
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Citation counts: TR Web of Science Citation Count  Cited 29 times in Thomson Reuters Web of Science Article | Citations
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Created: Wed, 26 Jan 2011, 09:56:34 EST by Dr Katrina Mcguigan on behalf of School of Biological Sciences