Important observations made managing carotid body tumours during a 25-year experience

Kruger, Allan J., Walker, Philip J., Foster, Wallace J., Jenkins, Jason S., Boyne, Nicholas S. and Jenkins, Julie (2010) Important observations made managing carotid body tumours during a 25-year experience. Journal of Vascular Surgery, 52 6: 1518-1523. doi:10.1016/j.jvs.2010.06.153


Author Kruger, Allan J.
Walker, Philip J.
Foster, Wallace J.
Jenkins, Jason S.
Boyne, Nicholas S.
Jenkins, Julie
Title Important observations made managing carotid body tumours during a 25-year experience
Journal name Journal of Vascular Surgery   Check publisher's open access policy
ISSN 0741-5214
1097-6809
Publication date 2010-12
Sub-type Article (original research)
DOI 10.1016/j.jvs.2010.06.153
Volume 52
Issue 6
Start page 1518
End page 1523
Total pages 6
Place of publication Philadelphia, PA, United States
Publisher Mosby
Collection year 2011
Language eng
Formatted abstract
Objectives: Our objective was to assess the short- and long-term outcome for patients after carotid body tumor (CBT) resection and discuss the potential pitfalls of the treatment.
Methods: An analysis was undertaken of all patients who underwent CBT resection at Royal Brisbane and Women's Hospital and Greenslopes Private Hospital between 1982 and 2007. Primary tumor characteristics, surgical technique, and outcomes were recorded and analyzed.
Results: A total of 49 consecutive CBT resections (2 recurrent tumors) were carried out in 39 patients (26 women [56%]) who were a mean age of 49 years (range, 17-75 years). A nontender neck mass was the presenting complaint in 85%, followed by screening in familial or contralateral tumors in 26%. Familial cases occurred in 11 patients (28%). There were no operative deaths. Complications occurred in 13 of the 49 operations (27%), predominantly temporary nerve palsies and were more likely to occur in tumors of large volume or in cases of removal of coexisting vagal tumors. Malignant disease was present in seven cases (15%). All patients have been followed-up postoperatively for a mean of 11 years (range, 2-26 years). Metachronous paragangliomas have been discovered in six patients, all with familial disease.
Conclusions: Early resection of carotid body tumors should be undertaken while still small to minimize the risk of neural injury, which increases with tumor size. In cases of bilateral CBT, we recommend that the smaller tumor be resected first, before the staged resection of the larger contralateral tumor. In familial or bilateral tumor cases, other synchronous and metachronous paragangliomas should be excluded. Mandatory lifelong follow-up is essential.
© 2010 by the Society for Vascular Surgery.

Keyword Paragangliomas
Carotid body tumor (CBT)
Preoperative Embolization
Chemodectoma
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: UQ Centre for Clinical Research Publications
Official 2011 Collection
School of Medicine Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 19 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 28 times in Scopus Article | Citations
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Created: Wed, 19 Jan 2011, 10:31:21 EST by Professor Philip Walker on behalf of UQ Centre for Clinical Research