Bacterial sulfite-oxidizing enzymes

Kappler, Ulrike (2011) Bacterial sulfite-oxidizing enzymes. Biochimica et Biophysica Acta - Bioenergetics, 1807 1: 1-10. doi:10.1016/j.bbabio.2010.09.004

Author Kappler, Ulrike
Title Bacterial sulfite-oxidizing enzymes
Journal name Biochimica et Biophysica Acta - Bioenergetics   Check publisher's open access policy
ISSN 0005-2728
Publication date 2011-01
Year available 2010
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.bbabio.2010.09.004
Volume 1807
Issue 1
Start page 1
End page 10
Total pages 10
Place of publication Amsterdam, Netherlands
Publisher Elsevier BV
Collection year 2011
Language eng
Formatted abstract
Enzymes belonging to the Sulfite Oxidase (SO) enzyme family are found in virtually all forms of life, and are especially abundant in prokaryotes as shown by analysis of available genome data. Despite this fact, only a limited number of bacterial SO family enzymes has been characterized in detail to date, and these appear to be involved in very different metabolic processes such as energy generation from sulfur compounds, host colonization, sulfite detoxification and organosulfonate degradation. The few characterized bacterial SO family enzymes also show an intriguing range of structural conformations, including monomeric, dimeric and heterodimeric enzymes with varying numbers and types of redox centres. Some of the bacterial enzymes even catalyze novel reactions such as dimethylsulfoxide reduction that previously had been thought not to be catalyzed by SO family enzymes. Classification of the SO family enzymes based on the structure of their Mo domain clearly shows that three distinct groups of enzymes belong to this family, and that almost all SOEs characterized to date are representatives of the same group.
The widespread occurrence and obvious structural and functional plasticity of the bacterial SO family enzymes make this an exciting field for further study, in particular the unraveling of the metabolic roles of the three enzyme groups, some of which appear to be associated almost exclusively with pathogenic microorganisms.
© 2010 Elsevier B.V.
Keyword Sulfite oxidation
Sulfur oxidizing bacteria
Molybdenum cofactor
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Available online 17 September 2010.

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2011 Collection
School of Chemistry and Molecular Biosciences
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Citation counts: TR Web of Science Citation Count  Cited 21 times in Thomson Reuters Web of Science Article | Citations
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Created: Sun, 09 Jan 2011, 00:10:10 EST