A rapid method for the simultaneous determination of the major metabolites of sulphasalazine in plasma

Shaw, P.N., Sivner, A..L, Aarons, L. and Houston, J.B. (1983) A rapid method for the simultaneous determination of the major metabolites of sulphasalazine in plasma. Journal of Chromatography - Biomedical Applications, 274 393-397. doi:10.1016/S0378-4347(00)84450-3


Author Shaw, P.N.
Sivner, A..L
Aarons, L.
Houston, J.B.
Title A rapid method for the simultaneous determination of the major metabolites of sulphasalazine in plasma
Journal name Journal of Chromatography - Biomedical Applications
ISSN 0378-4347
Publication date 1983-05
Sub-type Other
DOI 10.1016/S0378-4347(00)84450-3
Volume 274
Start page 393
End page 397
Total pages 5
Place of publication Amsterdam, Netherlands
Publisher Elsevier
Language eng
Abstract In the course of recent studies on the disposition of sulphasalazine in patients with large bowel disease we have developed a rapid, sensitive HPLC method for the determination of 5 aminosalicylate (AS), sulphapyridine (SP) and their acetylated metabolites (AcAS and AcSP). The advantage of the present assay over previous HPLC assays is that it measures all the metabolites simultaneously and consequently is more rapid.
Q-Index Code CX
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Other
Collection: School of Pharmacy Publications
 
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Created: Mon, 20 Dec 2010, 14:10:43 EST