The possible role of membrane lipids in the exceptionally long life of the short-beaked echidna, Tachyglossus aculeatus

Hubert, A.J., Beard, Lyn and Grigg, Gordon (2010) The possible role of membrane lipids in the exceptionally long life of the short-beaked echidna, Tachyglossus aculeatus. Australian Zoologist, 35 2: 154-159.


Author Hubert, A.J.
Beard, Lyn
Grigg, Gordon
Title The possible role of membrane lipids in the exceptionally long life of the short-beaked echidna, Tachyglossus aculeatus
Journal name Australian Zoologist   Check publisher's open access policy
ISSN 0067-2238
Publication date 2010-04
Year available 2010
Sub-type Article (original research)
Volume 35
Issue 2
Start page 154
End page 159
Total pages 6
Place of publication Sydney, NSW, Australia
Publisher Royal Zoological Society of New South Wales
Collection year 2011
Language eng
Abstract The short-beaked echidna (Tachyglossus aculeatus) is an exceptionally long-living mammal having a maximal lifespan of -50 years. This is about four times that predicted from its body mass and, consequently, its longevity quotient is ∼4.This longevity quotient is similar to two other exceptionally long-living mammalian species; the naked mole-rat (Heterocephalus glaber) and Homo sapiens. In recent times, the types of fats that make up cellular membrane have been implicated in the determination of a species' maximum lifespan. This modification of the oxidative stress theory of aging, which has been called the membrane pacemaker theory of aging, derives from the fact that polyunsaturated fats are very susceptible to lipid peroxidation whereas monounsaturated fats are resistant to peroxidation. As a test of the theory we measured the fatty acid composition of membrane lipids isolated from tissues of echidnas.We found that, as In the other long-living mammals, echidna membranes are more monounsaturated and less polyunsaturated than would be predicted from their body size and that the peroxidation Index of their membrane lipids is what their maximum longevity would predict.
Keyword Aging
Lipid peroxidation
Maximum life span
Membrane fatty acids
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Biological Sciences Publications
 
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Created: Tue, 14 Dec 2010, 11:06:18 EST by Gail Walter on behalf of School of Biological Sciences