Amniotic fluid volume and composition following experimental manipulations in sheep

Lingwood, Barbara E., Hardy, Kenneth J., Long, Jeffrey G., McPhee, Marion and Wintour, E. Marelyn (1980) Amniotic fluid volume and composition following experimental manipulations in sheep. Obstetrics and Gynecology, 56 4: 451-458.

Author Lingwood, Barbara E.
Hardy, Kenneth J.
Long, Jeffrey G.
McPhee, Marion
Wintour, E. Marelyn
Title Amniotic fluid volume and composition following experimental manipulations in sheep
Journal name Obstetrics and Gynecology   Check publisher's open access policy
ISSN 0029-7844
1873-233X
Publication date 1980-10
Sub-type Article (original research)
Volume 56
Issue 4
Start page 451
End page 458
Total pages 8
Place of publication Philadelphia, PA, United States
Publisher Lippincott Williams & Wilkins
Language eng
Abstract Twenty to thirty percent of amniotic fluid volume was replaced by isotonic solutions of saline, mannitol, or dextrose in chronically cannulated ovine fetuses. In all cases the sodium, potassium, and chloride concentrations returned to control values in 3 to 6 hours. Urea and creatinine behaved similarly in the saline and mannitol experiments, but rose above control values within 1 hour of dextrose replacement. Amniotic fluid volume increased with return of solute. Fetal urine drainage to the exterior abolished the rapid return of urea and creatinine concentrations in the dextrose experiments, although no changes in renal function occurred in any experiments. It was concluded that dextrose inhibited the exit of urea and creatinine from the amniotic compartment.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: UQ Centre for Clinical Research Publications
 
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Created: Tue, 07 Dec 2010, 09:33:29 EST