Auckland stroke outcomes study part 1: Gender, stroke types, ethnicity, and functional outcomes 5 years poststroke

Feigin, V. L., Barker-Collo, S., Parag, V., Senior, H., Lawes, C. M. M., Ratnasabapathy, Y., Glen, E. and For the ASTRO study group (2010) Auckland stroke outcomes study part 1: Gender, stroke types, ethnicity, and functional outcomes 5 years poststroke. Neurology, 75 18: 1597-1607. doi:10.1212/WNL.0b013e3181fb44b3

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Author Feigin, V. L.
Barker-Collo, S.
Parag, V.
Senior, H.
Lawes, C. M. M.
Ratnasabapathy, Y.
Glen, E.
For the ASTRO study group
Title Auckland stroke outcomes study part 1: Gender, stroke types, ethnicity, and functional outcomes 5 years poststroke
Journal name Neurology   Check publisher's open access policy
ISSN 0028-3878
Publication date 2010-11
Sub-type Article (original research)
DOI 10.1212/WNL.0b013e3181fb44b3
Volume 75
Issue 18
Start page 1597
End page 1607
Total pages 11
Place of publication Philadelphia, United States
Publisher Lippincott Williams & Wilkins
Collection year 2011
Language eng
Formatted abstract
Background: Studying long-term stroke outcomes including body functioning (neurologic and neuropsychological impairments) and activity limitations and participation is essential for long-term evidence-based rehabilitation and service planning, resource allocation, and improving health outcomes in stroke. However, reliable data to address these issues is lacking.
Methods: This study (February 2007-December 2008) sourced its participants from the population-based incidence study conducted in Auckland in 2002-2003. Participants completed structured self-administered questionnaires, and a face-to-face interview including a battery of neuropsychological tests. Logistic regression analysis was used to analyze associations between and within functional outcomes and their potential predictors.
Results: Of 418 5-year stroke survivors, two-thirds had good functional outcome in terms of neurologic impairment and disability (defined as modified Rankin Score <3), 22.5% had cognitive impairment indicative of dementia, 20% had experienced a recurrent stroke, almost 15% were institutionalized, and 29.6% had symptoms suggesting depression. Highly significant correlations were found between and within various measurements of body functioning (especially neuropsychological impairments), activity, and participation. Age, dependency, and depression were independently associated with most outcomes analyzed.
Conclusions: The strong associations between neuropsychological impairment and other functional outcomes and across various measurements of body functioning, activity, and participation justify utilizing a multidisciplinary approach to studying and managing long-term stroke outcomes. Observed gender and ethnic differences in some important stroke outcomes warrant further investigations.
Copyright © 2010 by AAN Enterprises, Inc. All rights reserved.
Keyword Quality-of-life
Geriatric depression scale
Clinical determinants
Community stroke
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Medicine Publications
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Created: Sun, 05 Dec 2010, 00:03:53 EST