Incidence of type 2 diabetes in Aboriginal Australians: An 11-year prospective cohort study

Wang, Zhiqiang, Hoy, Wendy and Si, Damin (2010) Incidence of type 2 diabetes in Aboriginal Australians: An 11-year prospective cohort study. BMC Public Health, 10 487: 1-5. doi:10.1186/1471-2458-10-487

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Author Wang, Zhiqiang
Hoy, Wendy
Si, Damin
Title Incidence of type 2 diabetes in Aboriginal Australians: An 11-year prospective cohort study
Journal name BMC Public Health   Check publisher's open access policy
ISSN 1471-2458
Publication date 2010-08-17
Sub-type Article (original research)
DOI 10.1186/1471-2458-10-487
Open Access Status DOI
Volume 10
Issue 487
Start page 1
End page 5
Total pages 5
Editor Melissa Norton
Place of publication London , U.K.
Publisher BioMed Central
Collection year 2011
Language eng
Formatted abstract
Background Diabetes is an important contributor to the health inequity between Aboriginal and non-Aboriginal Australians. This study aims to estimate incidence rates of diabetes and to assess its associations with impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) among Aboriginal participants in a remote community.

Methods Six hundred and eighty six (686) Aboriginal Australians aged 20 to 74 years free from diabetes at baseline were followed for a median of 11 years. During the follow-up period, new diabetes cases were identified through hospital records. Cox proportional hazards models were used to assess relationships of the incidence rates of diabetes with IFG, IGT and body mass index (BMI).

Results One hundred and twenty four (124) new diabetes cases were diagnosed during the follow up period. Incidence rates increased with increasing age, from 2.2 per 1000 person-years for those younger than 25 years to 39.9 per 1000 person-years for those 45-54 years. By age of 60 years, cumulative incidence rates were 49% for Aboriginal men and 70% for Aboriginal women. The rate ratio for developing diabetes in the presence of either IFG or IGT at baseline was 2.2 (95% CI: 1.5, 3.3), adjusting for age, sex and BMI. Rate ratios for developing diabetes were 2.2 (95% CI: 1.4, 3.5) for people who were overweight and 4.7 (95% CI: 3.0, 7.4) for people who were obese at baseline, with adjustment of age, sex and the presence of IFG/IGT.

Conclusions Diabetes incidence rates are high in Aboriginal people. The lifetime risk of developing diabetes among Aboriginal men is one in two, and among Aboriginal women is two in three. Baseline IFG, IGT and obesity are important predictors of diabetes.
© 2010 Wang et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keyword Impaired Glucose-tolerance
C-reactive protein
Middle-aged men
Fasting glucose
Metabolic syndrome
Lifetime risk
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Article number 487

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 16 times in Thomson Reuters Web of Science Article | Citations
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Created: Sun, 28 Nov 2010, 13:28:42 EST by Zhiqiang Wang on behalf of Medicine - Royal Brisbane and Women's Hospital