The willingness of women to participate in a long-term trial of hormone replacement therapy: A qualitative study using focus groups

Hepworth, J., Paine, B., Miles, H., Marley, J. and MacLennan, A. (2002) The willingness of women to participate in a long-term trial of hormone replacement therapy: A qualitative study using focus groups. Psychology, Health and Medicine, 7 4: 469-476. doi:10.1080/1354850021000015285


Author Hepworth, J.
Paine, B.
Miles, H.
Marley, J.
MacLennan, A.
Title The willingness of women to participate in a long-term trial of hormone replacement therapy: A qualitative study using focus groups
Journal name Psychology, Health and Medicine   Check publisher's open access policy
ISSN 1354-8506
1465-3966
Publication date 2002-01-01
Sub-type Article (original research)
DOI 10.1080/1354850021000015285
Volume 7
Issue 4
Start page 469
End page 476
Total pages 8
Place of publication Milton Park, Abingdon, Oxon, U.K.
Publisher Routledge
Language eng
Formatted abstract
The actual proportion of eligible people who participate in clinical trials is low. Consequently, a qualitative study of the willingness of women who are postmenopausal to participate in a long-term randomized control trial of hormone replacement therapy (HRT) designed to investigate the prevention of degenerative diseases was conducted. Focus group methodology was employed to explore the personal and social aspects of decision making about trial participation. Participants were randomly selected from the patient age-sex registers of four University of Adelaide general practices. Twenty-one women participated in four focus groups. The reasons for and against trial participation were examined using qualitative content analysis; (n = 18) women were unwilling to participate in the trial. The lack of perceived individual benefit, minimal altruism, the risk of breast cancer and side effects, not wanting to take unnecessary medication, a ten-year commitment, and negative experiences of HRT use, were the main reasons given for not entering the trial. Of the few women (n = 3) who clearly would enter the trial, free prescriptions and a positive history of using HRT were the main reasons for participation. The perceived disadvantages of clinical trials of HRT deter women from participating in a long-term clinical trial of HRT. An investment in education and information to eligible participants about both the risks and potential benefits of HRT may improve trial recruitment.
© Taylor & Francis Ltd
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Nursing, Midwifery and Social Work Publications
 
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Created: Fri, 19 Nov 2010, 02:19:05 EST by Allison Peacock on behalf of School of Nursing, Midwifery and Social Work