Airway and respiratory tissue mechanics in normal infants

Hall, G.L., Hantos, Z., Petak, F., Wildhaber, J.H., Tiller, K., Burton, P.R. and Sly, P.D. (2000) Airway and respiratory tissue mechanics in normal infants. American Journal of Respiratory and Critical Care Medicine, 162 4: 1397-1402.

Author Hall, G.L.
Hantos, Z.
Petak, F.
Wildhaber, J.H.
Tiller, K.
Burton, P.R.
Sly, P.D.
Title Airway and respiratory tissue mechanics in normal infants
Journal name American Journal of Respiratory and Critical Care Medicine   Check publisher's open access policy
ISSN 1073-449X
Publication date 2000-10
Sub-type Article (original research)
Volume 162
Issue 4
Start page 1397
End page 1402
Total pages 6
Place of publication New York, NY, United States
Publisher American Thoracic Society
Language eng
Formatted abstract
Low-frequency respiratory impedance (Zrs) was measured by applying a forcing signal, between 0.5 and 21 Hz at a transrespiratory pressure of 20 cm H2O, in a cross-sectional study of 37 normal infants. A model containing an airway resistance (Raw) and inertance (law) and a tissue damping (G) and elastance (H) was fitted to the individual Zrs. Forced expiratory volume in 0.5 second (FEV0.5) was determined using the raised volume rapid thoracic compression technique. Multivariate regression analysis was used to analyze the relationships between the lung function parameters and length. Both airway and tissue parameters showed a decreasing quadratic relationship with increasing length. FEV0.5 showed an increasing cubic relationship with length. A family history of asthma was found to have a negative effect on Raw, H, and FEV0.5.
Keyword Pulmonary function
Forced expitation
Young children
Chest wall
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
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Created: Wed, 17 Nov 2010, 11:28:52 EST