Focusing on optic tectum circuitry through the lens of genetics

Nevin, Linda, Robles, Estuardo, Baier, Herwig and Scott, Ethan K. (2010) Focusing on optic tectum circuitry through the lens of genetics. BMC Biology, 8 Article number 126: 1-10. doi:10.1186/1741-7007-8-126

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Author Nevin, Linda
Robles, Estuardo
Baier, Herwig
Scott, Ethan K.
Title Focusing on optic tectum circuitry through the lens of genetics
Journal name BMC Biology   Check publisher's open access policy
ISSN 1741-7007
Publication date 2010-09-28
Year available 2010
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1186/1741-7007-8-126
Open Access Status DOI
Volume 8
Issue Article number 126
Start page 1
End page 10
Total pages 10
Place of publication London, England
Publisher BioMed Central
Collection year 2011
Language eng
Abstract The visual pathway is tasked with processing incoming signals from the retina and converting this information into adaptive behavior. Recent studies of the larval zebrafish tectum have begun to clarify how the 'micro-circuitry' of this highly organized midbrain structure filters visual input, which arrives in the superficial layers and directs motor output through efferent projections from its deep layers. The new emphasis has been on the specific function of neuronal cell types, which can now be reproducibly labeled, imaged and manipulated using genetic and optical techniques. Here, we discuss recent advances and emerging experimental approaches for studying tectal circuits as models for visual processing and sensorimotor transformation by the vertebrate brain. © 2010 Nevin et al; licensee BioMed Central Ltd.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2011 Collection
School of Biomedical Sciences Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 45 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 44 times in Scopus Article | Citations
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Created: Tue, 16 Nov 2010, 10:21:34 EST by Dr Ethan Scott on behalf of School of Biomedical Sciences