Schistosomiasis elimination: lessons from the past guide the future

Gray, DJ, McManus, DP, Li, YS, Williams, GM, Bergquist, R and Ross, AG (2010) Schistosomiasis elimination: lessons from the past guide the future. Lancet Infectious Diseases, 10 10: 733-736. doi:10.1016/S1473-3099(10)70099-2

Author Gray, DJ
McManus, DP
Li, YS
Williams, GM
Bergquist, R
Ross, AG
Title Schistosomiasis elimination: lessons from the past guide the future
Journal name Lancet Infectious Diseases   Check publisher's open access policy
ISSN 1473-3099
Publication date 2010-10
Sub-type Article (original research)
DOI 10.1016/S1473-3099(10)70099-2
Volume 10
Issue 10
Start page 733
End page 736
Total pages 4
Place of publication London, United Kingdom
Publisher The Lancet Publishing Group
Collection year 2011
Language eng
Abstract Schistosomiasis is a major neglected tropical disease, with more than 200 million people infected and close to 800 million at risk. The disease burden is estimated to exceed 70 million disability-adjusted life-years. The anthelmintic drug praziquantel is highly effective in killing adult schistosome worms, but it is unable to kill developing schistosomes and so does not prevent reinfection. As a result, current praziquantel-based control programmes in Asia and sub-Saharan Africa are not effective or sustainable in the long term. The control of neglected tropical diseases, including schistosomiasis, is a funding priority for several donor agencies, with over US$350 million committed until 2013. Here we put forward an argument that donor funds would be more effectively spent on the development of a multi-faceted, integrated control programme, which would have a greater and longer lasting effect on disease transmission than the current chemotherapy-based programmes. The development of a transmission-blocking vaccine is also of great importance. A multi-faceted integrated control programme that incorporates a vaccine, even if only partly effective, has the potential to eliminate schistosomiasis. This integrated-approach model has the potential to improve the health of a billion of the world's poorest people and its effect cannot be underestimated. © 2010 Elsevier Ltd.
Keyword Neglected tropical diseases
Global health
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Public Health Publications
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Created: Sun, 31 Oct 2010, 00:04:26 EST