Body mass index and breast size in women: Same or different genes?

Wade, Tracey D., Zhu, Gu and Martin, Nicholas G. (2010) Body mass index and breast size in women: Same or different genes?. Twin Research and Human Genetics, 13 5: 450-454. doi:10.1375/twin.13.5.450


Author Wade, Tracey D.
Zhu, Gu
Martin, Nicholas G.
Title Body mass index and breast size in women: Same or different genes?
Journal name Twin Research and Human Genetics   Check publisher's open access policy
ISSN 1832-4274
Publication date 2010-10
Sub-type Article (original research)
DOI 10.1375/twin.13.5.450
Volume 13
Issue 5
Start page 450
End page 454
Total pages 5
Place of publication Bowen Hills, QLD, Australia
Publisher Australian Academic Press
Collection year 2011
Language eng
Abstract The objective of the current study was to investigate the heritability of breast size and the degree to which this heritability is shared with BMI. In a sample of 1010 females twins (mean age 35 years; SD = 2.1; range 28-40), self-report data pertaining to bra cup size and body mass index (BMI) was collected in the context of self-report data and an interview relating to disordered eating respectively. In a sample of 348 complete twin pairs who completed data collection (226 MZ pairs and 122 DZ pairs and 360 incomplete pairs (170 MZ and 190 DZ)), we found that the heritability of bra cup size was 56%. Of this genetic variance, one third is in common with genes influencing body mass index, and two thirds (41% of total variance) is unique to breast size, with some directional evidence of non-additive genetic variation. The implications of these findings with respect to previous research linking breast size with reproductive potential are discussed. © Copyright 2011 Elsevier B.V.
Keyword Breast size
Body mass index
Heritability
Bivariate Cholesky
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Medicine Publications
 
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Created: Sun, 31 Oct 2010, 00:01:05 EST