Association of psychiatric disorders, asthma and lung function in early adulthood

Hayatbakhsh, Mohammad R., Najman, Jake M., Clavarino, Alexandra, Bor, William, Williams, Gail M. and O'Callaghan, Michael J. (2010) Association of psychiatric disorders, asthma and lung function in early adulthood. Journal of Asthma, 47 7: 786-791. doi:10.3109/02770903.2010.489141

Author Hayatbakhsh, Mohammad R.
Najman, Jake M.
Clavarino, Alexandra
Bor, William
Williams, Gail M.
O'Callaghan, Michael J.
Title Association of psychiatric disorders, asthma and lung function in early adulthood
Journal name Journal of Asthma   Check publisher's open access policy
ISSN 0277-0903
Publication date 2010-09
Sub-type Article (original research)
DOI 10.3109/02770903.2010.489141
Volume 47
Issue 7
Start page 786
End page 791
Total pages 6
Place of publication New York, N.Y.
Publisher Marcel Dekker
Collection year 2011
Language eng
Formatted abstract
Objective. To examine the association between psychiatric disorders, asthma, and lung function in young adults. Study Design. Data were from the Mater–University of Queensland Study of Pregnancy (MUSP). The study was based on 2443 young adults (1193 male and 1250 female) for whom data were available on psychiatric disorders, asthma, and respiratory function. Life time and last 12 months’ generalized anxiety, panic, posttraumatic stress disorder (PTSD), and depressive disorders were assessed using a computerised version of the Composite International Diagnostic Interview (CIDI-Auto). A Spirobank G spirometer system was used to measure forced vital capacity (FVC), forced expiratory volume in one second (FEV1), and forced expiratory flow between 25% and 75% of forced vital capacity (FEF25–75%). Results. Participants with mental health disorders were more likely to have experienced asthma before or to use asthma medication at 21 years. However, for both males and females, life time and last 12 months’ experience of generalized anxiety, panic, PTSD, and depressive disorders were not statistically significantly associated with FVC, FEV1, and FEF25–75%, except a modest association with major depressive disorders for males. Conclusion. There is an association between mental health and asthma, but the relationship between mental health and lung function appeared to be confounded by the respondent's gender. More narrowly based prospective studies are required to determine the causal pathway between mental disorders and asthma.
© 2010 Informa Healthcare USA, Inc.

Keyword Asthma
Lung function
Psychiatric Disorder
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

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Created: Sun, 24 Oct 2010, 00:12:51 EST