Malignant sacrococcygeal germ cell tumour in an adult

Smithers, B. Mark, Theile, David E., Dickinson, Ian C., Thomson, Damien B. and Axelsen, Roy A. (1996) Malignant sacrococcygeal germ cell tumour in an adult. Australian and New Zeland Journal of Surgery, 66 3: 185-189. doi:10.1111/j.1445-2197.1996.tb01156.x

Author Smithers, B. Mark
Theile, David E.
Dickinson, Ian C.
Thomson, Damien B.
Axelsen, Roy A.
Title Malignant sacrococcygeal germ cell tumour in an adult
Journal name Australian and New Zeland Journal of Surgery   Check publisher's open access policy
ISSN 0004-8682
Publication date 1996-03
Sub-type Article (original research)
DOI 10.1111/j.1445-2197.1996.tb01156.x
Volume 66
Issue 3
Start page 185
End page 189
Total pages 5
Place of publication Richmond, Vic., Australia
Publisher Wiley-Blackwell Publishing
Language eng
Abstract In adults, malignant sacrococcygeal germ cell tumour is a rare cause for a presacral tumour, with only 17 cases having been reported in the literature since 1907. We report the case of a 34 year old male who presented with a 6 month history of symptoms relating to a malignant presacral tumour which required en bloc excision including the lower sacrum and rectum. He died with lung and mediastinal metastasis 7 months following surgical excision and adjuvant chemotherapy using Cisplatin, Bleomycin and Etoposide. Prior to his death, he had a severe polyarthritis of his peripheral joints and evidence of hypertrophic osteo-arthropathy. The literature indicates that adults with these tumours have a poor prognosis, with only one reported long-term survivor. Surgical excision offers the only chance of cure, with the role of adjuvant therapy not having been defined because of the small numbers.
Keyword Hypertrophic osteo-arthropathy
Malignant sacrococcygeal germ cell tumour
Presacral tumour
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
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Created: Mon, 18 Oct 2010, 09:19:11 EST