Desmoplastic melanoma: Patterns of recurrence

Smithers, B. Mark, McLeod, G. Roderick and Little, John H. (1992) Desmoplastic melanoma: Patterns of recurrence. World Journal of Surgery, 16 2: 186-190. doi:10.1007/BF02071519

Author Smithers, B. Mark
McLeod, G. Roderick
Little, John H.
Title Desmoplastic melanoma: Patterns of recurrence
Journal name World Journal of Surgery   Check publisher's open access policy
ISSN 0364-2313
Publication date 1992-03
Sub-type Article (original research)
DOI 10.1007/BF02071519
Volume 16
Issue 2
Start page 186
End page 190
Total pages 5
Place of publication Secaucus, NJ, United States
Publisher Springer
Language eng
Formatted abstract
Desmoplastic melanoma is a rare type of malignant melanoma, recognized since 1971. Other variants of desmoplastic melanoma include neural transforming melanoma and neurotropic melanoma.
The pathology and clinical features of 58 patients whose tumor had the features of desmoplastic melanoma, neural transforming melanoma, and neurotropic melanoma, either separately or in combination, were examined to assess patterns of recurrent disease. The tumor was situated on the head and neck in 41% of patients and was amelanotic in 71% of patients. There was an associated superficial melanoma in 48% of patients. There was a combination of the 3 histologic patterns, commonly found in the 1 melanoma. Local recurrence occurred in 29% of patients and malignant cranial neuropathies were documented in 4 patients. Nineteen percent of patients have died from disseminated disease. Neurotropic melanomas had a lower incidence of visceral recurrence. Desmoplastic and neural transforming melanomas had similar rates of local and visceral recurrence.
When this specific variant of melanoma is compared with larger series of malignant melanoma in general, they appear to be more advanced locally, with a higher incidence of local recurrence. When considered in relation to the thicker nondesmoplastic melanomas, the survival is no worse and may be more favorable.
Surgeons should excise the primary tumor and local recurrences with wide margins and adopt close follow-up. On the head and neck, symptoms and signs relating to trigeminal or facial nerve innervation may herald a developing malignant cranial neuropathy.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
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Created: Mon, 18 Oct 2010, 09:18:57 EST