Desmoplastic, neural transforming and neurotropic melanoma: A review of 45 cases

Smithers, B. M., McLeod, G. R. and Little, J. H. (1990) Desmoplastic, neural transforming and neurotropic melanoma: A review of 45 cases. Australian and New Zealand Journal of Surgery, 60 12: 967-972. doi:10.1111/j.1445-2197.1990.tb07515.x


Author Smithers, B. M.
McLeod, G. R.
Little, J. H.
Title Desmoplastic, neural transforming and neurotropic melanoma: A review of 45 cases
Journal name Australian and New Zealand Journal of Surgery   Check publisher's open access policy
ISSN 0004-8682
Publication date 1990-12
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1111/j.1445-2197.1990.tb07515.x
Volume 60
Issue 12
Start page 967
End page 972
Total pages 6
Place of publication Richmond, Vic., Australia
Publisher Wiley-Blackwell Publishing
Language eng
Abstract An analysis of the clinicopathological features of 45 cases of desmoplastic, neural transforming and neurotropic melanoma assessed by a single pathologist are reported. The age range of 27 males and 18 females was 17-88 years. Twenty primary lesions (44%) were on the head and neck and fourteen (31%) were on the trunk. Thirty lesions (67%) were amelanotic). The initial clinical diagnosis was incorrect for 16 patients. Mean thickness was 4.5mm. Recurrence occurred in 17 patients (38%). Local recurrence has occurred in 12 patients. This was related to a primary where: pathological diagnosis was incorrect; excision was less than 1 cm; the site was on the head and neck; Clarke level was V; and Breslow thickness was > 4 mm. Four patients had cranial nerve neuropathies due to recurrent neurotropic melanoma. Four patients are alive with inoperable disease and five have died from disseminated melanoma. These tumours can be difficult to recognize clinically and pathologically, with poor results if not adequately treated primarily. Therefore, the need for surgeons to be aware of this tumour and its clinicopathological features is important. Close follow-up is essential.
Keyword Desmoplastic
Melanoma
Neural transforming
Neurotropic
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Medicine Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 67 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 64 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Mon, 18 Oct 2010, 09:18:53 EST