Radiation therapy for nodal disease in malignant melanoma

Burmeister, B. H., Smithers, B. M., Poulsen, M., McLeod, G. R., Bryant, G., Tripcony, L. and Thorpe, C. (1995) Radiation therapy for nodal disease in malignant melanoma. World Journal of Surgery, 19 3: 369-371. doi:10.1007/BF00299160


Author Burmeister, B. H.
Smithers, B. M.
Poulsen, M.
McLeod, G. R.
Bryant, G.
Tripcony, L.
Thorpe, C.
Title Radiation therapy for nodal disease in malignant melanoma
Journal name World Journal of Surgery   Check publisher's open access policy
ISSN 0364-2313
1432-2323
Publication date 1995-05
Sub-type Article (original research)
DOI 10.1007/BF00299160
Volume 19
Issue 3
Start page 369
End page 371
Total pages 3
Place of publication Secaucus, NJ, United States
Publisher Springer
Language eng
Abstract Radiation therapy has been widely used for palliative management of inoperable metastatic malignant melanoma. For patients with nodal disease, response rates of approximately 70% have been reported. There are limited data concerning the role of adjuvant irradiation following therapeutic lymph node dissection. In this review, 57 patients with isolated resectable and nonresectable nodal disease have been treated with radiation. The overall response rate is 84% for bulky disease. Large fractions are beneficial. The median disease-free survivals were 11 months after adjuvant treatment and 7 months for those with inoperable disease. The median overall survivals were 20 months and 18 months, respectively. Local control in long-term survivors was excellent. Sixty-five percent of patients developed distant metastases. There is a need for additional studies with the use of adjuvant radiation therapy following lymph node dissection.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Mon, 18 Oct 2010, 09:15:40 EST