Nuclear organization of cholinergic, putative catecholaminergic and serotonergic systems in the brains of five microchiropteran species

Kruger, Jean-Leigh, Dell, Leigh-Anne, Bhagwandin, Adhil, Jillani, Ngalla E., Pettigrew, John D. and Manger, Paul R. (2010) Nuclear organization of cholinergic, putative catecholaminergic and serotonergic systems in the brains of five microchiropteran species. Journal of Chemical Neuroanatomy, 40 3: 210-222. doi:10.1016/j.jchemneu.2010.05.007


Author Kruger, Jean-Leigh
Dell, Leigh-Anne
Bhagwandin, Adhil
Jillani, Ngalla E.
Pettigrew, John D.
Manger, Paul R.
Title Nuclear organization of cholinergic, putative catecholaminergic and serotonergic systems in the brains of five microchiropteran species
Journal name Journal of Chemical Neuroanatomy   Check publisher's open access policy
ISSN 0891-0618
1873-6300
Publication date 2010-11
Sub-type Article (original research)
DOI 10.1016/j.jchemneu.2010.05.007
Volume 40
Issue 3
Start page 210
End page 222
Total pages 13
Place of publication Amsterdam, Netherlands
Publisher Elsevier BV
Collection year 2011
Language eng
Subject C1
1109 Neurosciences
Formatted abstract
The current study describes, using immunohistochemical methods, the nuclear organization of the cholinergic, catecholaminergic and serotonergic systems within the brains of five microchiropteran species. For the vast majority of nuclei observed, direct homologies are evident in other mammalian species; however, there were several distinctions in the presence or absence of specific nuclei that provide important clues regarding the use of the brain in the analysis of chiropteran phylogenetic affinities. Within the five species studied, three specific differences (presence of a parabigeminal nucleus, dorsal caudal nucleus of the ventral tegmental area and the absence of the substantia nigra ventral) found in two species from two different families (Cardioderma cor; Megadermatidae, and Coleura afra; Emballonuridae), illustrates the diversity of microchiropteran phylogeny and the usefulness of brain characters in phylogenetic reconstruction. A number of distinct differences separate the microchiropterans from the megachiropterans, supporting the diphyletic hypothesis of chiropteran phylogenetic origins. These differences phylogenetically align the microchiropterans with the heterogenous grouping of insectivores, in contrast to the alignment of megachiropterans with primates. The consistency of the changes and stasis of neural characters with mammalian phylogeny indicate that the investigation of the microchiropterans as a sister group to one of the five orders of insectivores to be a potentially fruitful area of future research. © 2010 Elsevier B.V. All rights reserved.
Keyword Microbat
Chiroptera
Neuromodulatory systems
Diphyly
Evolution
Mammalia
Morphological characteristics
Rousettus Aegyptiacus
Basal Forebrain
Mammalian Brain
Neurons
Cells
Chiroptera
Midbrain
Bats
Acetyltransferase
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
Queensland Brain Institute Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 16 times in Thomson Reuters Web of Science Article | Citations
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Created: Sun, 17 Oct 2010, 00:08:00 EST