Natural diversity in flowering responses of Arabidopsis thaliana caused by variation in a tandem gene array

Rosloski, Sarah Marie, Jali, Sathya Shiela, Balasubramanian, Sureshkumar, Weigel, Detlef and Grbic, Vojislava (2010) Natural diversity in flowering responses of Arabidopsis thaliana caused by variation in a tandem gene array. Genetics, 186 1: 263-276. doi:10.1534/genetics.110.116392


Author Rosloski, Sarah Marie
Jali, Sathya Shiela
Balasubramanian, Sureshkumar
Weigel, Detlef
Grbic, Vojislava
Title Natural diversity in flowering responses of Arabidopsis thaliana caused by variation in a tandem gene array
Formatted title
Natural diversity in flowering responses of Arabidopsis thaliana caused by variation in a tandem gene array
Journal name Genetics   Check publisher's open access policy
ISSN 0016-6731
1943-2631
Publication date 2010-09
Sub-type Article (original research)
DOI 10.1534/genetics.110.116392
Volume 186
Issue 1
Start page 263
End page 276
Total pages 24
Editor Elizabeth W. Jones
Place of publication Austin, Tex., U.S.A.
Publisher Genetics Society of America
Collection year 2011
Language eng
Subject C1
970106 Expanding Knowledge in the Biological Sciences
060412 Quantitative Genetics (incl. Disease and Trait Mapping Genetics)
Formatted abstract
Tandemly arrayed genes that belong to gene families characterize genomes of many organisms. Gene duplication and subsequent relaxation of selection can lead to the establishment of paralogous cluster members that may evolve along different trajectories. Here, we report on the structural variation in MADS AFFECTING FLOWERING 2 (MAF2) gene, one member of the tandemly duplicated cluster of MADS-box-containing transcription factors in Arabidopsis thaliana. The altered gene structure at the MAF2 locus is present as a moderate-frequency polymorphism in Arabidopsis and leads to the extensive diversity in transcript patterns due to alternative splicing. Rearrangements at the MAF2 locus are associated with an early flowering phenotype in BC5 lines. The lack of suppression of flowering time in a MAF2-insertion line expressing the MAF2-specific artificial miRNA suggests that these MAF2 variants are behaving as loss-of-function alleles. The variation in gene architecture is also associated with segregation distortion, which may have facilitated the spread and the establishment of the corresponding alleles throughout the Eurasian range of the A. thaliana population. Copyright
© 2010 by the Genetics Society of America.
Keyword Quantitative trait loci
Disease resistence genes
Inbred line populations
Unequal crossing-over
Time genes
Protein families
Dna-sequence
Copy-number
Genomic data
A-thaliana
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Biological Sciences Publications
 
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Created: Sun, 10 Oct 2010, 00:05:26 EST