First outbreak of PVL-positive nonmultiresistant MRSA in a neonatal ICU in Australia: Comparison of MALDI-TOF and SNP-plus-binary gene typing

Schlebusch, S., Price, G. R., Hinds, S., Nourse, C., Schooneveldt, J. M., Tilse, M. H., Liley, H. G., Wallis, T., Bowling, F., Venter, D. and Nimmo, G. R. (2010) First outbreak of PVL-positive nonmultiresistant MRSA in a neonatal ICU in Australia: Comparison of MALDI-TOF and SNP-plus-binary gene typing. European Journal of Clinical Microbiology and Infectious Diseases, 29 10: 1311-1314. doi:10.1007/s10096-010-0995-y


Author Schlebusch, S.
Price, G. R.
Hinds, S.
Nourse, C.
Schooneveldt, J. M.
Tilse, M. H.
Liley, H. G.
Wallis, T.
Bowling, F.
Venter, D.
Nimmo, G. R.
Title First outbreak of PVL-positive nonmultiresistant MRSA in a neonatal ICU in Australia: Comparison of MALDI-TOF and SNP-plus-binary gene typing
Journal name European Journal of Clinical Microbiology and Infectious Diseases   Check publisher's open access policy
ISSN 0934-9723
1435-4373
Publication date 2010-10-01
Sub-type Article (original research)
DOI 10.1007/s10096-010-0995-y
Volume 29
Issue 10
Start page 1311
End page 1314
Total pages 4
Place of publication Heidelberg, Germany
Publisher Springer
Collection year 2011
Language eng
Abstract The purpose of this brief report is to describe the first outbreak of a community-associated nonmultiresistant and PVL-positive MRSA strain (CC30) in a neonatal intensive care unit in Australia. The utility of matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI-TOF-MS) for microbial typing is compared with single nucleotide polymorphism (SNP) plus binary gene analysis. The composite correlation index analysis of the MALDI-TOF-MS data demonstrated the similar inter-strain relatedness found with the SNP-plus-binary gene typing used to confirm the outbreak. The evolving spread of MRSA emphasizes the importance of surveillance, infection control vigilance and the ongoing investigation of rapid typing methods for MRSA. © 2010 Springer-Verlag.
Keyword Resistant staphylococcus-aureus
Flight mass-spectometry
Nosocomial outbreak
Infections
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published under Brief Report

 
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Created: Sun, 03 Oct 2010, 10:06:30 EST