Anterior-posterior bending strength at the tibial shaft increases with physical activity in boys: Evidence for non-uniform geometric adaptation

Macdonald, H. M., Cooper, D. M. L. and McKay, H. A. (2009) Anterior-posterior bending strength at the tibial shaft increases with physical activity in boys: Evidence for non-uniform geometric adaptation. Osteoporosis International, 20 1: 61-70.


Author Macdonald, H. M.
Cooper, D. M. L.
McKay, H. A.
Title Anterior-posterior bending strength at the tibial shaft increases with physical activity in boys: Evidence for non-uniform geometric adaptation
Journal name Osteoporosis International  (ERA 2012 Listed)    (ERA 2010 Rank A)   Check publisher's open access policy
Publication date 2009-01
Sub-type Article
DOI 10.1007/s00198-008-0636-9
Volume number 20
Issue number 1
ISSN 0937-941X; 1433-2965
Start page 61
End page 70
Total pages 10
Place of publication London, U.K.
Publisher Springer International
Language eng
Subject 1103 Clinical Sciences
Formatted abstract Summary: We investigated bone structural adaptations to a 16-month school-based physical activity intervention in 202 young boys using a novel analytical method for peripheral quantitative computed tomography scans of the tibial mid-shaft. Our intervention effectively increased bone bending strength in the anterior-posterior plane as estimated with the maximum second moment of area (Imax).

Introduction: We previously reported positive effects of a physical activity intervention on peripheral quantitative computed tomography (pQCT)-derived bone strength at the tibial mid-shaft in young boys. The present study further explored structural adaptations to the intervention using a novel method for pQCT analysis.

Methods: Participants were 202 boys (aged 9-11 years) from 10 schools randomly assigned to control (CON, 63 boys) and intervention (INT, 139 boys) groups. INT boys participated in 60 min/week of classroom physical activity, including a bone-loading program. We used ImageJ to process pQCT images of the tibial mid-shaft and determine the second moments of area (Imax, Imin) and cortical area (CoA) and thickness (CTh) by quadrant (anterior, medial, lateral, posterior). We defined quadrants according to pixel coordinates about the centroid. We used mixed linear models to compare change in bone outcomes between groups.

Results: The INT boys had a 3% greater gain in Imax than the CON boys (p = 0.04) and tended to have a greater gain in Imin (∼2%, NS). Associated with the greater gain in Imax was a slightly greater (NS) gain (1-1.4%) in CoA and CTh in the anterior, medial, and posterior (but not lateral) quadrants.

Conclusion: Our results suggest regional variation in bone adaptation consistent with patterns of bone formation induced by anterior-posterior bending loads.
© 2008 International Osteoporosis Foundation and National Osteoporosis Foundation.
Keyword Bone
Peripheral QCT
Children
Physical activity
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article
Collections: Excellence in Research Australia (ERA) - Collection
School of Human Movement Studies Publications
 
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