The recipient side of TRALI: The role of patient neutrophils

Fung, L. (2007). The recipient side of TRALI: The role of patient neutrophils. In: 18th Regional Congress of the International Society for Blood Transfusion, Asia, Hanoi, Vietnam, (135-140). 10-13 November 2007. doi:10.1111/j.1751-2824.2007.00129.x


Author Fung, L.
Title of paper The recipient side of TRALI: The role of patient neutrophils
Conference name 18th Regional Congress of the International Society for Blood Transfusion, Asia
Conference location Hanoi, Vietnam
Conference dates 10-13 November 2007
Journal name ISBT Science Series   Check publisher's open access policy
Place of Publication Oxford
Publisher Wiley-Blackwell
Publication Year 2007
Sub-type Fully published paper
DOI 10.1111/j.1751-2824.2007.00129.x
ISBN *****************
ISSN 1751-2816
1751-2824
Volume 2
Issue 2
Start page 135
End page 140
Total pages 6
Language eng
Abstract/Summary Transfusion-related acute lung injury (TRALI) is a serious and potentially fatal complication of blood transfusions. The fact that TRALI has been the top cause of transfusion-related mortalities in the USA over the last 3 years (2004–06) [1] provides irrefutable evidence of the clinical significance of this syndrome. From this perspective, its importance in transfusion complications surpasses that of blood-borne viruses and bacterial infections. Despite this, we still do not clearly understand the pathophysiology and pathogenesis of TRALI. This paper presents a TRALI patient or recipient perspective by discussing how thorough serological investigations can be utilized to provide evidence that patient neutrophils are the target cell and to identify the implicated donation/s when there are multiple associated donations.
Keyword Laboratory investigation
Serology
TRALI
Transfusion recipient
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

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Created: Wed, 22 Sep 2010, 09:45:47 EST