Protein expression systems for non-pathogenic Kinetoplastidae

Alexandrov, Kirill and Grün, Mathias (2001). Protein expression systems for non-pathogenic Kinetoplastidae. WO/2001/032896.

Creator Alexandrov, Kirill
Grün, Mathias
Patent title Protein expression systems for non-pathogenic Kinetoplastidae
Date of issue 2001-10-05
Patent number WO/2001/032896
Language eng
Subjects 0604 Genetics
Formatted abstract
The object of the present invention is a method of recombinant protein production in vitro with cultivated non pathogenic Kinetoplastidae parasites (Leishmania tarentolae, Crithidia fasciculata, Wallaceina inconstans) (former Proteomonas inconstans), (Leptomonas collos, Leptomonas sp. Cfm, Leptomonas sp. Nfm or Leptomonas seymouri). This includes description of cultivation conditions for several species that allow large scale growth of these organisms on cheap media. The method of the invention includes strategies and construct description for generation of stably transfected organisms capable of expression of recombinant proteins.
Additional Notes International Application No.: PCT/EP2000/010794 IPC: C12N 15/85 (2006.01) Applicants: JENA BIOSCIENCE GMBH [DE/DE]; Loebstedter Strasse 78, 07749 Jena (DE) (All Except US). ALEXANDROV, Kirill [DE/DE]; (DE) (US Only). GRUN, Mathias [DE/US]; (US) (US Only).

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Created: Wed, 15 Sep 2010, 09:22:38 EST by Laura McTaggart on behalf of Aust Institute for Bioengineering & Nanotechnology