Remission induced by an elemental diet in small bowel Crohn's disease

Sanderson, I.R., Udeen, S., Davies, P.S.W., Savage, M.O. and Walkersmith, J.A. (1987) Remission induced by an elemental diet in small bowel Crohn's disease. Archives of Disease in Childhood, 62 2: 123-127. doi:10.1136/adc.62.2.123


Author Sanderson, I.R.
Udeen, S.
Davies, P.S.W.
Savage, M.O.
Walkersmith, J.A.
Title Remission induced by an elemental diet in small bowel Crohn's disease
Journal name Archives of Disease in Childhood   Check publisher's open access policy
ISSN 0003-9888
1468-2052
Publication date 1987-02
Sub-type Article (original research)
DOI 10.1136/adc.62.2.123
Volume 62
Issue 2
Start page 123
End page 127
Total pages 5
Place of publication London, England
Publisher BMJ Publishing Group
Language eng
Subject 1114 Paediatrics and Reproductive Medicine
1108 Medical Microbiology
Abstract Seventeen children with active Crohn's disease of the small intestine were entered into a randomised control trial comparing the efficacy of an elemental diet with that of a high dose steroid regimen. Eight children received an elemental diet (Flexical) through a nasogastric tube for six weeks, followed by reintroduction of food over six weeks during which the Flexical was stopped. Seven children were given intramuscular adrenocorticotrophic hormone followed by oral prednisolone with sulphasalazine. Two children were withdrawn from the trial. The elemental diet was equally effective in inducing an improvement in Lloyd-Still disease activity index, erythrocyte sedimentation rate, C reactive protein and albumin concentrations, and body weight as the high dose steroid regimen. Linear growth, assessed from height velocity over six months, was significantly greater in the children receiving an elemental diet.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Wed, 08 Sep 2010, 09:37:00 EST