Total body water in children with congenital heart disease, before and after cardiac surgery

Mitchell, I.M., Davies, P.S.W., Pollock, J.C.S. and Jamieson, M.P.G. (1995) Total body water in children with congenital heart disease, before and after cardiac surgery. Journal of Thoracic And Cardiovascular Surgery, 110 3: 633-640. doi:10.1016/S0022-5223(95)70094-3


Author Mitchell, I.M.
Davies, P.S.W.
Pollock, J.C.S.
Jamieson, M.P.G.
Title Total body water in children with congenital heart disease, before and after cardiac surgery
Journal name Journal of Thoracic And Cardiovascular Surgery   Check publisher's open access policy
ISSN 0022-5223
1097-685X
Publication date 1995-09
Sub-type Article (original research)
DOI 10.1016/S0022-5223(95)70094-3
Volume 110
Issue 3
Start page 633
End page 640
Total pages 8
Place of publication New York, N.Y. U.S.A.
Publisher Elsevier
Language eng
Subject 1111 Nutrition and Dietetics
1114 Paediatrics and Reproductive Medicine
Formatted abstract
The aim of this study was to measure total body water in children with congenital heart disease before and after cardiac surgery and to compare the results of deuterium and 18oxygen dilution methods. Seventeen children (aged 4 to 33 months) were given aliquots of isotopically labeled water 1 week before and 6 hours after cardiac surgery. Isotope equilibration and analysis of the declining enrichment of daily urine samples allowed calculation of the total body water content. Before operation, total body water was significantly elevated (p < 0.001, Wilcoxon test); after operation it fell to approximately normal values. This finding is in contrast to those of previous reports, but may be explained in that the method used for calculation depended on measurements taken over a 7-day period rather than on a single measurement of isotope dilution as used elsewhere. Nevertheless, these results do suggest that surgery can correct the preoperative fluid overload. Comparison of deuterium and 18oxygen dilution methods showed a 2% to 2.5% overestimation of the total body water content with deuterium sampling.
Keyword Doubly-labeled-water
Bioelectrical Impedance
Infants
Operations
Validation
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Wed, 08 Sep 2010, 09:35:54 EST