Energy expenditure in children with congenital heart disease, before and after cardiac surgery

MitchellL, I.M., Davies, P.S.W., Day, J.M.E., Pollock, J.C.S. and Jamison, M.P.G. (1994). Energy expenditure in children with congenital heart disease, before and after cardiac surgery. In: Journal of Thoracic and Cardiovascular Surgery. 73rd Annual Meeting of the American-Association-for-Thoracic-Surgery, Chicago, IL, U.S.A., (374-380). 25-28 April, 1993.


Author MitchellL, I.M.
Davies, P.S.W.
Day, J.M.E.
Pollock, J.C.S.
Jamison, M.P.G.
Title of paper Energy expenditure in children with congenital heart disease, before and after cardiac surgery
Conference name 73rd Annual Meeting of the American-Association-for-Thoracic-Surgery
Conference location Chicago, IL, U.S.A.
Conference dates 25-28 April, 1993
Proceedings title Journal of Thoracic and Cardiovascular Surgery   Check publisher's open access policy
Journal name Journal of Thoracic and Cardiovascular Surgery   Check publisher's open access policy
Place of Publication New York, N.Y. U.S.A.
Publisher Elsevier
Publication Year 1994
Sub-type Fully published paper
ISSN 0022-5223
1097-685X
Volume 107
Issue 2
Start page 374
End page 380
Total pages 6
Language eng
Formatted Abstract/Summary
Failure to thrive is a common feature of children with congenital heart disease. Whether this is the result of poor nutrition or an abnormally high basal metabolic rate is unknown, yet the state of nutrition has a profound effect on the metabolic response to injury and strongly influences the outcome of surgical treatment. The aim of this study was therefore to measure the preoperative and postoperative energy requirements of children with congenital heart disease. Eighteen children (aged 4 to 33 months) were given two oral doses of doubly labeled water (H218O and 2H2O), the first 1 week before operation and the second 6 hours after the end of cardiac surgery. By measuring the relative loss of each isotope from the body water pool, we were able to calculate the rate of carbon dioxide production and therefore total energy expenditure. In five patients, energy expenditure was clearly elevated, suggesting that a raised basal metabolic rate is an important factor in the observed failure to thrive in at least a proportion of such children. Postoperatively, energy expenditure fell to values below normal for healthy children (not having an operation), which suggests that the stress of surgery leads to smaller energy requirements than have previously been thought.
Subjects 1103 Clinical Sciences
1114 Paediatrics and Reproductive Medicine
Keyword Total Parenteral-nutrition
Doubly Labeled Water
Surgical Patients
Body-composition
Malnutrition
Protein
Infants
Injury
Weight
Risk
Q-Index Code E1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Conference Paper
Collection: School of Medicine Publications
 
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Created: Wed, 08 Sep 2010, 09:35:50 EST