Acinetobacter baumannii: Emergence of a successful pathogen

Peleg, Anton Y., Seifert, Harald and Paterson, David L. (2008) Acinetobacter baumannii: Emergence of a successful pathogen. Clinical Microbiology Reviews, 21 3: 538-582.


Author Peleg, Anton Y.
Seifert, Harald
Paterson, David L.
Title Acinetobacter baumannii: Emergence of a successful pathogen
Formatted title Acinetobacter baumannii: Emergence of a successful pathogen
Journal name Clinical Microbiology Reviews   Check publisher's open access policy
ISSN 0893-8512
1070-6305
1098-6618
Publication date 2008-07
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1128/CMR.00058-07
Volume 21
Issue 3
Start page 538
End page 582
Total pages 45
Place of publication Washington, DC, United States
Publisher American Society for Microbiology
Language eng
Subject 1108 Medical Microbiology
Formatted abstract Acinetobacter baumannii has emerged as a highly troublesome pathogen for many institutions globally. As a consequence of its immense ability to acquire or upregulate antibiotic drug resistance determinants, it has justifiably been propelled to the forefront of scientific attention. Apart from its predilection for the seriously ill within intensive care units, A. baumannii has more recently caused a range of infectious syndromes in military personnel injured in the Iraq and Afghanistan conflicts. This review details the significant advances that have been made in our understanding of this remarkable organism over the last 10 years, including current taxonomy and species identification, issues with susceptibility testing, mechanisms of antibiotic resistance, global epidemiology, clinical impact of infection, host-pathogen interactions, and infection control and therapeutic considerations.
Keyword Multidrug-resistant acinetobacter
Metallo-Beta-Lactamase
Intensive care unit
Gram negative bacteria
In vitro activity
Critically ill patients
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Medicine Publications
 
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