Disseminated donovanosis (granuloma inguinale) causing spinal cord compression: Case report and review of donovanosis involving bone

Paterson, David L. (1998) Disseminated donovanosis (granuloma inguinale) causing spinal cord compression: Case report and review of donovanosis involving bone. Clinical Infectious Diseases, 26 2: 379-383. doi:10.1086/516327


Author Paterson, David L.
Title Disseminated donovanosis (granuloma inguinale) causing spinal cord compression: Case report and review of donovanosis involving bone
Journal name Clinical Infectious Diseases   Check publisher's open access policy
ISSN 1058-4838
Publication date 1998-02-01
Sub-type Article (original research)
DOI 10.1086/516327
Volume 26
Issue 2
Start page 379
End page 383
Total pages 5
Place of publication Chicago Ill., U.S.A.
Publisher University of Chicago Press.
Language eng
Subject 1103 Clinical Sciences
1117 Public Health and Health Services
Abstract Donovanosis is a genital ulcer disease that occasionally has extragenital manifestations. This report describes a case of disseminated donovanosis in a 54-year-old woman from northern Australia who had subsequent thoracic vertebral osteomyelitis and spinal cord compression. Malignancy and vertebral tuberculosis were the major differential diagnoses. The patient had no genital lesions at the time of diagnosis of extragenital donovanosis but had undergone a hysterectomy, thus raising the possibility of prior disease of the uterine cervix (most previous cases have been associated with primary cervical disease). Despite treatment with doxycycline, she had no significant neurological improvement. Donovanosis disseminated to bone has been reported in 18 cases in the last 55 years. Awareness of donovanosis in the differential diagnosis of osteomyelitis and prompt pelvic examinations enabling early diagnosis of occult cervical disease are the most important measures in preventing morbidity and mortality due to disseminated donovanosis.
Keyword Oral Cavity
Azithromycin
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: UQ Centre for Clinical Research Publications
 
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Created: Wed, 08 Sep 2010, 03:05:16 EST