High-compliance tuberculosis treatment programme in a rural community

Wilkinson, D. (1994) High-compliance tuberculosis treatment programme in a rural community. Lancet, 343 8898: 647-648. doi:10.1016/S0140-6736(94)92640-9

Author Wilkinson, D.
Title High-compliance tuberculosis treatment programme in a rural community
Journal name Lancet   Check publisher's open access policy
ISSN 0140-6736
Publication date 1994-03-12
Sub-type Other
DOI 10.1016/S0140-6736(94)92640-9
Volume 343
Issue 8898
Start page 647
End page 648
Total pages 2
Place of publication London, England
Publisher Lancet Publishing Group
Language eng
Subject 1108 Medical Microbiology
1117 Public Health and Health Services
Abstract The global tuberculosis epidemic is being fuelled by dual infection with human immunodeficiency virus type I. Short-course chemotherapy is effective but usually fails for operational reasons. A community-based treatment programme of twice-weekly fully-supervised treatment is described in which 89% of surviving patients completed treatment under programme conditions. Half the patients were successfully supervised by non-health workers. New approaches are needed to combat the global tuberculosis epidemic. This article describes a tuberculosis (TB) treatment program which achieved a high rate of compliance and completion by close supervision in a supervised intermittent ambulatory treatment (SIAT) program in Zululand, South Africa. After patients had reported to a hospital for sickness and were subsequently diagnosed positive for TB, they were aligned with a SIAT center and a TB treatment site was selected. In most cases these assignments were chosen by the patient as a matter of personal convenience. In 1993, 36% of the adults diagnosed with TB were also infected with human immunodeficiency virus type 1 (HIV-1). Supervisors were selected to oversee each treatment site and were given responsibility for ensuring that patients took their medication. Supervisors also kept treatment records which were inspected by trained medical personnel. In cases where patients missed treatment appointments, the trained medical personnel would investigate. The SIAT program included a 6-month chemotherapy treatment procedure conducted at supervised sites which included hospital-run clinics and non-hospital operated health care sites. The author reports that a full and complete course of chemotherapy is a critical aspect in the management of TB. He reports that the SIAT program ensures a high compliance rate and that a high completion-of-treatment rate (60% vs. 18% pre-SIAT) is possible when using a community-based SIAT program against TB.
Q-Index Code CX
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Other
Collection: School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 127 times in Thomson Reuters Web of Science Article | Citations
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Created: Tue, 07 Sep 2010, 13:04:25 EST