Raised prostaglandin levels in the third stage of labor

Sellers, S.M., Hodgson, H.T., Mitchell, M.D., Anderson, A. B. M. and Turnbull, A. C. (1982) Raised prostaglandin levels in the third stage of labor. American Journal of Obstetrics and Gynecology, 144 2: 209-212.

Author Sellers, S.M.
Hodgson, H.T.
Mitchell, M.D.
Anderson, A. B. M.
Turnbull, A. C.
Title Raised prostaglandin levels in the third stage of labor
Journal name American Journal of Obstetrics and Gynecology   Check publisher's open access policy
ISSN 0002-9378
Publication date 1982
Sub-type Article (original research)
Volume 144
Issue 2
Start page 209
End page 212
Total pages 4
Place of publication St. Louis, Mo. U.S.A.
Publisher Mosby
Language eng
Subject 1103 Clinical Sciences
1114 Paediatrics and Reproductive Medicine
Abstract Serial measurements of maternal peripheral plasma concentrations of 13,14-dihydro-15-keto-prostaglandin F (PGFM) and oxytocin were made during the three stages of labor and in the immediate puerperium. PGFM levels increased as labor progressed, and reached maximal levels before placental separation had occurred. The mean value in the second stage of labor was significantly higher than that in the first stage (p < 0.01); similarly, the value 5 minutes after delivery, before expulsion of the placenta, was significantly greater than that in the second stage of labor (p < 0.01). There was no significant difference between the mean PGFM concentration at placental separation and the level 5 minutes after delivery or in the second stage of labor. Two hours after delivery of the placenta, PGFM levels were not significantly different from values observed in the first stage of labor. Peripheral plasma concentrations of oxytocin did not change significantly at any stage of labor or 2 hours post partum. These results suggest that prostaglandins have a role in the third stage of labor, and this finding may have important clinical implications.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: UQ Centre for Clinical Research Publications
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Created: Thu, 26 Aug 2010, 13:16:22 EST