Arachidonate lipoxygenase activity in human fetal lung

Saeed, Sheikh A. and Mitchell, Murray D. (1982) Arachidonate lipoxygenase activity in human fetal lung. European Journal of Pharmacology, 78 3: 389-391. doi:10.1016/0014-2999(82)90047-4

Author Saeed, Sheikh A.
Mitchell, Murray D.
Title Arachidonate lipoxygenase activity in human fetal lung
Journal name European Journal of Pharmacology   Check publisher's open access policy
ISSN 0014-2999
Publication date 1982-03-12
Sub-type Other
DOI 10.1016/0014-2999(82)90047-4
Volume 78
Issue 3
Start page 389
End page 391
Total pages 3
Place of publication The Netherlands
Publisher Elsevier
Language eng
Subject 1103 Clinical Sciences
1114 Paediatrics and Reproductive Medicine
Abstract The results are suggestive of the presence of lipoxygenase activity in human fetal lung. Since human fetal lung produces PG's and since the lipoxygenase products, HETE and its labile hydroperoxy precursor, HPETE have been proposed as potentially important mediators for many biological activities, the formation of these compounds including PGs early in gestation is suggestive of a role for lipoxygenase metabolites in the pathophysiology of the human fetal lung. Modification of arachidonate lipoxygenase activity in the fetal and neonatal lung may have profound effects upon responses to pathological stimuli by modulating leukocyte infiltration and by effecting bronchoconstriction.
Q-Index Code CX
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Other
Collection: UQ Centre for Clinical Research Publications
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Citation counts: TR Web of Science Citation Count  Cited 19 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 10 times in Scopus Article | Citations
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Created: Thu, 26 Aug 2010, 13:12:58 EST