Topographic differences in amniotic fluid concentrations of prostanoids in women in spontaneous labor at term

Romero, R., Gonzalez, R., Baumann, P., Behnke, E., Rittenhouse, L., Barberio, D., Cotton, D.B. and Mitchell, M.D. (1994) Topographic differences in amniotic fluid concentrations of prostanoids in women in spontaneous labor at term. Prostaglandins Leukotrienes and Essential Fatty Acids, 50 2: 97-104. doi:10.1016/0952-3278(94)90154-6


Author Romero, R.
Gonzalez, R.
Baumann, P.
Behnke, E.
Rittenhouse, L.
Barberio, D.
Cotton, D.B.
Mitchell, M.D.
Title Topographic differences in amniotic fluid concentrations of prostanoids in women in spontaneous labor at term
Journal name Prostaglandins Leukotrienes and Essential Fatty Acids   Check publisher's open access policy
ISSN 0952-3278
1532-2823
Publication date 1994-02
Sub-type Article (original research)
DOI 10.1016/0952-3278(94)90154-6
Volume 50
Issue 2
Start page 97
End page 104
Total pages 8
Place of publication Edinburgh ; New York
Publisher Churchill Livingstone
Language eng
Subject 0604 Genetics
1114 Paediatrics and Reproductive Medicine
Formatted abstract
These studies were designated to determine if there are differences in prostanoid concentrations between amniotic fluid (AF) retrieved transvaginally from the membrane forebag (lower or forebag compartment) and fluid retrieved by transabdominal amniocentesis from the 'upper compartment' in women in labor. Fluid was retrieved from 53 women in active labor who underwent transabdominal and transvaginal amniocentesis. Fluid was assayed for prostaglandin E2 (PGE2) and prostaglandin F(2α) (PGF(2α)), 13,14-dihydro-15-keto-prostaglandin F(2α) (PGFM), thromboxane B2 (TXB2), and 6-keto-prostaglandin F(1α) (6-k-PGF(1α)) using sensitive and specific radioimmunoassays. Concentrations of all prostanoids measured were significantly higher in fluid retrieved by transvaginal than transabdominal amniocentesis; the magnitude of the increase (measured as the ratio of concentrations in the lower/upper compartment) was higher for PGF(2α) and TXB2 than for the other prostanoids measured; for each prostanoid measured, there was a significant correlation between the concentration in the upper and lower compartment.
Keyword Human Parturition
Prostaglandins
Endotoxin
Plasma
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: UQ Centre for Clinical Research Publications
 
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Created: Thu, 26 Aug 2010, 13:11:35 EST