Specific production of prostaglandin E by human amnion in vitro

Mitchell, M.D., Bibby, J., Hicks, B.R. and Turnbull, A.C. (1978) Specific production of prostaglandin E by human amnion in vitro. Prostaglandins, 15 2: 377-382. doi:10.1016/0090-6980(78)90177-6

Author Mitchell, M.D.
Bibby, J.
Hicks, B.R.
Turnbull, A.C.
Title Specific production of prostaglandin E by human amnion in vitro
Journal name Prostaglandins   Check publisher's open access policy
ISSN 0090-6980
Publication date 1978-02
Sub-type Article (original research)
DOI 10.1016/0090-6980(78)90177-6
Volume 15
Issue 2
Start page 377
End page 382
Total pages 6
Place of publication Stoneham, Ma., U.S.A.
Publisher Butterworths
Language eng
Subject 1103 Clinical Sciences
1114 Paediatrics and Reproductive Medicine
Abstract Prostaglandin production by intra-uterine human tissues has been investigated using a method of tissue superfusion. Tissues were obtained at elective Caesarean section and after spontaneous vaginal delivery. It was found that all the tissues studied (amnion chorion, decidua and placenta) produced more prostaglandin E (PGE) and 13,14-dihydro-15-keto-prostaglandin F (PGFM: the major circulating metabolite of prostaglandin F) than prostaglandin F (PGF). Amnion produced significantly more PGE (but not PGF or PGFM) than any other tissue. Prostaglandin production by each tissue was similar whether it was taken at elective Caesarean section or after spontaneous vaginal delivery.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: UQ Centre for Clinical Research Publications
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Created: Thu, 26 Aug 2010, 13:01:59 EST