Genetic strain and reproductive status affect endometrial fatty acid concentrations

Meier, S., Peterson, A.J., Mitchell, M.D., Littlejohn, M., Walker, C.G. and Roche, J.R. (2009) Genetic strain and reproductive status affect endometrial fatty acid concentrations. Journal of Dairy Science, 92 8: 3723-3730. doi:10.3168/jds.2009-2047


Author Meier, S.
Peterson, A.J.
Mitchell, M.D.
Littlejohn, M.
Walker, C.G.
Roche, J.R.
Title Genetic strain and reproductive status affect endometrial fatty acid concentrations
Journal name Journal of Dairy Science   Check publisher's open access policy
ISSN 0022-0302
1525-3198
Publication date 2009-08
Sub-type Article (original research)
DOI 10.3168/jds.2009-2047
Volume 92
Issue 8
Start page 3723
End page 3730
Total pages 8
Place of publication Champaign, Ill., U.S.A.
Publisher American Dairy Science Association
Language eng
Subject 1103 Clinical Sciences
06 Biological Sciences
Abstract Poor reproductive performance limits cow longevity in seasonal, pasture-based dairy systems. Few differences in ovarian dynamics have been reported in different strains of Holstein-Friesian cows, implying that the uterine environment may be a key component determining reproductive success. To test the hypothesis that the uterine environment differs among genetic strains of the Holstein-Friesian cow, endometrial fatty acids (FA) were analyzed from New Zealand (NZ), and North American (NA) Holstein-Friesian cows. The effect of reproductive status was also investigated, with cows from both Holstein-Friesian strains slaughtered on either d 17 of the estrous cycle (termed cyclic) or d 17 of pregnancy (after embryo transfer; termed pregnant). Endometrial tissues were collected from 22 cows (NZ pregnant, n = 6; NZ cyclic, n = 4; NA pregnant, n = 6; NA cyclic, n = 6), and FA composition was analyzed. Daily plasma progesterone concentrations, milk production, milk FA composition, body weight, and body condition score were determined. Milk yield (4% fat-corrected milk) was similar for the NZ (28.5 kg/d) and NA (29.3 kg/d; SE 2.07 kg/d) cows, but NZ cows had a greater mean milk fat percentage. Mean plasma progesterone concentrations were significantly greater in NZ cows. Plasma progesterone concentrations were similar in the pregnant and cyclic groups. Mean length of the trophoblast recovered from the pregnant cows (NZ: 20.8 ± 2.84 cm; NA: 27.9 ± 10.23 cm) was not affected by genetic strain. Endometrial tissues from NZ cows contained greater concentrations of C17:0, C20:3n-3, and total polyunsaturated FA. The endome- tria from pregnant cows contained greater concentrations of C17:0, C20:2, and C20:3n-6, and less C20:1, C20:2, C20:5n-3. The observed changes in endometrial FA between Holstein-Friesian cows of different genetic origins or reproductive states may reflect differences in endometrial function and may affect reproductivefunction. © American Dairy Science Association, 2009.
Keyword Endometrium
Fatty Acid
Holstein-Friesian strain
Pregnancy
Holstein-Friesian Cow
Dairy-cows
Prostaglandin Biosynthesis
Arachidonic-acid
Pasture
Lipids
Cattle
Expression
Systems
Q-Index Code C1
Q-Index Status Provisional Code

Document type: Journal Article
Sub-type: Article (original research)
Collection: UQ Centre for Clinical Research Publications
 
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Created: Thu, 26 Aug 2010, 13:00:29 EST