Prostaglandins in human milk

Lucas, A. and Mitchell, M.D. (1980) Prostaglandins in human milk. Archives of Disease in Childhood, 55 12: 950-952. doi:10.1136/adc.55.12.950

Author Lucas, A.
Mitchell, M.D.
Title Prostaglandins in human milk
Journal name Archives of Disease in Childhood   Check publisher's open access policy
ISSN 0003-9888
Publication date 1980-12
Sub-type Article (original research)
DOI 10.1136/adc.55.12.950
Volume 55
Issue 12
Start page 950
End page 952
Total pages 3
Place of publication London, England
Publisher BMJ Publishing Group
Language eng
Subject 1103 Clinical Sciences
1114 Paediatrics and Reproductive Medicine
Abstract Prostaglandins E and F have been shown to be present in breast milk in over 100 times the concentrations found in adult plasma. The ratio of the concentration of the principal circulating metabolite of prostaglandin F (13,14-dihydro-15-ketoprostaglandin F) to prostaglandin F itself is low (0.3 to 0.5, compared with 15.8 in adult plasma), implying that prostaglandins may have a relatively long half-life in milk. In addition inactive metabolites of thromboxane A2 and prostacyclin are also found in significant amounts. It is speculated that milk prostaglandins play a role in modulating neonatal physiology - for example, gut motility.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: UQ Centre for Clinical Research Publications
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Citation counts: TR Web of Science Citation Count  Cited 47 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 26 times in Scopus Article | Citations
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Created: Thu, 26 Aug 2010, 12:58:34 EST