Inhibition of prostaglandin synthase by maternal plasma factor(s) in early human pregnancy

Brennecke, S. P., Lenton, E. A., Turnbull, A. C. and Mitchell, M. D. (1982) Inhibition of prostaglandin synthase by maternal plasma factor(s) in early human pregnancy. British Journal of Obstetrics and Gynaecology, 89 8: 612-616. doi:10.1111/j.1471-0528.1982.tb04714.x


Author Brennecke, S. P.
Lenton, E. A.
Turnbull, A. C.
Mitchell, M. D.
Title Inhibition of prostaglandin synthase by maternal plasma factor(s) in early human pregnancy
Journal name British Journal of Obstetrics and Gynaecology   Check publisher's open access policy
ISSN 0306-5456
Publication date 1982-08
Sub-type Article (original research)
DOI 10.1111/j.1471-0528.1982.tb04714.x
Volume 89
Issue 8
Start page 612
End page 616
Total pages 5
Place of publication London, England
Publisher Elsevier
Language eng
Subject 1103 Clinical Sciences
1114 Paediatrics and Reproductive Medicine
Abstract Using an enzyme incubation-radioimmunoassay technique, we have tested the hypothesis that an increase in a maternal plasma factor(s) that inhibits prostaglandin synthase (EC 1.14.99.1) is responsible for the suppression of decidual prostaglandin production that occurs in early human pregnancy. Measurements made on serial maternal samples failed to reveal any significant increase in plasma inhibitory activity as this time, and it was concluded that the conceptus achieved the reduction in prostaglandin synthesis by a mechanism other than a systemically mediated direct inhibition of decidual prostaglandin synthase.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: UQ Centre for Clinical Research Publications
 
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Created: Thu, 26 Aug 2010, 12:48:37 EST