Urinary catecholamine levels and response to group cognitive behaviour therapy in depression

Oei, Tian P. S., Dingle, Genevieve A. and McCarthy, Molly (2010) Urinary catecholamine levels and response to group cognitive behaviour therapy in depression. Behavioural and Cognitive Psychotherapy, 38 4: 479-483. doi:10.1017/S1352465810000093

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Author Oei, Tian P. S.
Dingle, Genevieve A.
McCarthy, Molly
Title Urinary catecholamine levels and response to group cognitive behaviour therapy in depression
Journal name Behavioural and Cognitive Psychotherapy   Check publisher's open access policy
ISSN 1469-1833
Publication date 2010-07
Sub-type Article (original research)
DOI 10.1017/S1352465810000093
Volume 38
Issue 4
Start page 479
End page 483
Total pages 5
Place of publication London
Publisher Cambridge University Press
Collection year 2011
Language eng
Formatted abstract
Aim: The aim was to investigate whether high catecholamine (CA) excreters would respond less well to a group cognitive behaviour therapy (CBT) treatment for depression than others.

: A sample of 70 adults with depression symptoms participated in a 12-week course of group CBT. Participants’ 24 hour urinary catecholamine levels at pre-therapy and post-therapy were used to classify them as High (N = 10); Low (N = 33) or Mixed (N = 27) according to a cut-off one standard deviation above a published mean for healthy adults. Beck Depression Inventory (BDI) and cognitions questionnaire (Automatic Thoughts Questionnaire; Beck Hopelessness Scale and Dysfunctional Attitudes Scale) were used.

Results: Repeated measures ANOVA analyses showed an equal rate of mood improvement in all three groups over the course of CBT, despite the fact that the High excreters were on average more depressed throughout the study. Changes in depression symptoms were mirrored by improvements in cognitive measures in the three catecholamine groups.

Conclusion: This study indicates that adults showing a biological marker of depression (elevated catecholamine levels) are equally able to benefit from CBT treatment as adults without this marker.
© British Association for Behavioural and Cognitive Psychotherapies 2010

Keyword Catecholamines
Cognitive behaviour therapy
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Psychology Publications
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Citation counts: TR Web of Science Citation Count  Cited 7 times in Thomson Reuters Web of Science Article | Citations
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Created: Sun, 08 Aug 2010, 00:07:49 EST