Nicotine does not enhance basic semantic priming

Holmes, Anna D., Chenery, Helen J. and Copland, David A. (2010) Nicotine does not enhance basic semantic priming. Psychopharmacology, 211 3: 259-265. doi:10.1007/s00213-010-1886-8

Author Holmes, Anna D.
Chenery, Helen J.
Copland, David A.
Title Nicotine does not enhance basic semantic priming
Journal name Psychopharmacology   Check publisher's open access policy
ISSN 0033-3158
Publication date 2010-08
Sub-type Article (original research)
DOI 10.1007/s00213-010-1886-8
Volume 211
Issue 3
Start page 259
End page 265
Total pages 7
Place of publication Berlin
Publisher Springer
Collection year 2011
Language eng
Formatted abstract
Rationale: Utilising a cognitively demanding strategy-based priming paradigm, we recently observed that acute transdermal nicotine selectively influenced controlled semantic processing but not related-word links within semantic memory per se as reported by Holmes et al. (Int J Neuropsychopharmacol 11:389-399, 2008).

The current study employed a less cognitively demanding priming paradigm to investigate whether nicotine influences the activation/access of links within semantic memory, and if the selective nicotinic influence on controlled but not automatic semantic processing could also be observed with these more general priming procedures.

Methods: Transdermal nicotine patches (7 mg/24 h) were administered to healthy young adults in a double-blind, placebo-controlled, crossover design. The automatic priming task (∈n∈∈=∈18) had a low relatedness proportion (RP) and was presented at a short stimulus onset asynchrony (SOA), while the controlled priming task (∈n∈∈=∈18) had a high RP and long SOA.

The patterns of priming effects indicated that automatic and controlled processing were operating for the respective tasks. However, a nicotinic influence on semantic processing was not evident for either task, nor was interplay of nicotine and relatedness observed.

Conclusions: Together, the findings from the previous and current study suggest that an influence of nicotine on semantic processing may only emerge when effortful controlled processing is invoked. Furthermore, the findings suggest that nicotinic modulation of links within semantic memory may only be mediated by mnemonic processes. © 2010 Springer-Verlag.  © 2010 Springer-Verlag.
Keyword Nicotine
Semantic priming
Cognitive demand
Visual Word Recognition
Spreading Activation
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: UQ Centre for Clinical Research Publications
Official 2011 Collection
School of Health and Rehabilitation Sciences Publications
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Citation counts: TR Web of Science Citation Count  Cited 1 times in Thomson Reuters Web of Science Article | Citations
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Created: Sun, 01 Aug 2010, 00:01:08 EST