Vector competence of Australian mosquitoes for chikungunya virus

Van Den Hurk, AF, Hall-Mendelin, S, Pyke, AT, Smith, GA and Mackenzie, JS (2010) Vector competence of Australian mosquitoes for chikungunya virus. Vector-Borne and Zoonotic Diseases, 10 5: 489-495. doi:10.1089/vbz.2009.0106


Author Van Den Hurk, AF
Hall-Mendelin, S
Pyke, AT
Smith, GA
Mackenzie, JS
Title Vector competence of Australian mosquitoes for chikungunya virus
Journal name Vector-Borne and Zoonotic Diseases   Check publisher's open access policy
ISSN 1530-3667
1557-7759
Publication date 2010-06
Year available 2009
Sub-type Article (original research)
DOI 10.1089/vbz.2009.0106
Volume 10
Issue 5
Start page 489
End page 495
Total pages 7
Place of publication New Rochelle, NY, U.S.A.
Publisher Mary Ann Liebert
Collection year 2011
Language eng
Formatted abstract
Chikungunya virus (CHIKV) is a globally emerging arbovirus responsible for unprecedented outbreaks in the western Indian Ocean, the Indian subcontinent and Italy. To assess the receptivity of Australia to CHIKV, we exposed 10 Australian mosquito species to a 2006 strain of CHIKV isolated from a viremic traveler from Mauritius. In susceptibility trials, the infectious dose required to infect 50% of the mosquitoes was 100.6 cell culture infectious dose (CCID)50/mosquito for Aedes procax, 101.7 CCID50/mosquito for Aedes albopictus, 102.1 CCID50/mosquito for Aedes vigilax, and 102.6 CCID50/mosquito for Aedes aegypti and Aedes notoscriptus. When exposed to blood meals containing between 103.5 and 104.1 CCID50/mosquito of CHIKV, infection rates in these five species, plus Coquillettidia linealis, were ≥81%. Subsequent transmission rates ranged between 20% for Ae. notoscriptus and 76% for Ae. vigilax. In contrast, Culex spp. were poor laboratory vectors, with infection and dissemination rates ≤20% and ≤12%, respectively. Although Australia has efficient laboratory vectors, the role a mosquito species plays in potential CHIKV transmission cycles will also depend on its geographical and temporal abundance, longevity, and association with humans.
© Copyright 2010, Mary Ann Liebert, Inc..

Keyword Aedes
Chikungunya
Mosquito(es)
Transmission
Vector-borne
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Online Ahead of Print: October 30, 2009

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Chemistry and Molecular Biosciences
 
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Created: Sun, 04 Jul 2010, 00:00:07 EST