Morphological and molecular characterisation of Echinococcus granulosus in livestock and humans in Punjab, Pakistan

Latif, Asma A., Tanveer, Akhtar, Maqbool, Azhar, Siddiqi, Nasir, Kyaw-Tanner, Myat and Traub, Rebecca J. (2010) Morphological and molecular characterisation of Echinococcus granulosus in livestock and humans in Punjab, Pakistan. Veterinary Parasitology, 170 1-2: 44-49. doi:10.1016/j.vetpar.2010.02.003


Author Latif, Asma A.
Tanveer, Akhtar
Maqbool, Azhar
Siddiqi, Nasir
Kyaw-Tanner, Myat
Traub, Rebecca J.
Title Morphological and molecular characterisation of Echinococcus granulosus in livestock and humans in Punjab, Pakistan
Formatted title
Morphological and molecular characterisation of Echinococcus granulosus in livestock and humans in Punjab, Pakistan
Journal name Veterinary Parasitology   Check publisher's open access policy
ISSN 0304-4017
1873-2550
Publication date 2010-05-28
Sub-type Article (original research)
DOI 10.1016/j.vetpar.2010.02.003
Volume 170
Issue 1-2
Start page 44
End page 49
Total pages 6
Editor C. Genchi
D.K. Howe
M.A. Taylor
R.C.A. Thompson
Place of publication Amsterdam, Netherlands
Publisher Elsevier
Collection year 2011
Language eng
Formatted abstract
Cystic echinococcus poses an important economic and public health problem to Pakistan. Our study determined the prevalence and genotypes of Echinococcus present in domestic livestock and humans in Punjab, Pakistan. Out of 39,738 animals examined, 6.67% of animals were found infected. The prevalence and fertility of hydatid cysts was highest in camels (prevalence 17.29%; proportion fertile 95%), followed by sheep (prevalence 7.52%; proportion fertile 86.4%), buffalo (prevalence 7.19%; proportion fertile 84.3%), goats (prevalence 5.48%; proportion fertile 79.09%) and cattle (prevalence 5.18%; proportion fertile 75.25%). Phylogenetic analysis of the cytochrome oxidase-1 gene revealed that the common sheep strain (G1) and buffalo strain (G3) are cycling among livestock in Punjab and that these strains are highly adapted to goats, camels and cattle. Both human cysts were found to belong to the common sheep strain (G1) of E. granulosus, reinforcing this strain has the most potential for zoonotic transfer. Both morphological and molecular results support earlier studies suggesting that Echinococcus of sheep and buffalo origin is phenotypically and genetically similar which adds further evidence to support its recognition as one species viz, Echinococcus granulosus sensu stricto.
© 2010 Published by Elsevier B.V.
Keyword Echinococcus granulosus
PCR
Pakistan
Hydatid
Humans
Cytochrome oxidase
Origin
Camel
Hydatidosis
Genotype
Region
Cattle
China
Iran
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Veterinary Science Publications
 
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Created: Sun, 27 Jun 2010, 00:00:09 EST