Quantifying the duration of pre-diabetes

Bertram, Melanie Y. and Vos, Theo (2010) Quantifying the duration of pre-diabetes. Australian and New Zealand Journal of Public Health, 34 3: 311-314. doi:10.1111/j.1753-6405.2010.00532.x

Author Bertram, Melanie Y.
Vos, Theo
Title Quantifying the duration of pre-diabetes
Journal name Australian and New Zealand Journal of Public Health   Check publisher's open access policy
ISSN 1326-0200
Publication date 2010-06
Sub-type Article (original research)
DOI 10.1111/j.1753-6405.2010.00532.x
Volume 34
Issue 3
Start page 311
End page 314
Total pages 4
Place of publication Richmond, VIC, Australia
Publisher Wiley-Blackwell Publishing Asia
Collection year 2011
Language eng
Formatted abstract
Objective: Interventions for individuals with pre-diabetes are efficacious, however, identification of people with pre-diabetes does not occur in Australia. This study aims to calculate the duration of pre-diabetes, in order to provide supporting evidence for a screening program.

Methods: We carried out a systematic review and random effects meta-analysis to identify if an increased risk of mortality is present in people with pre-diabetes. The result of this meta-analysis as well as information on prevalence, remission of pre-diabetes and transition to diabetes from an Australian cohort study, were used in the software program DisMod to calculate duration.

Results: From 2,578 articles identified, 11 studies met the inclusion criteria. The pooled relative risk of all-cause mortality was 1.26 (1.17-1.34) with no sign of heterogeneity between the studies. The average duration of pre-diabetes was 8.5 years in males aged 30+ and 10.3 years in females aged 30+.

Conclusions: The duration of pre-diabetes in Australia is long enough to warrant a screening program. The finding is robust to sensitivity testing of very large variations in the epidemiological parameters.

Implications: If the interventions following screening are shown to be cost-effective, a strong rationale for the implementation of a screening program exists.
© Public Health Association of Australia.

Keyword Pre-diabetes
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Public Health Publications
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Citation counts: TR Web of Science Citation Count  Cited 15 times in Thomson Reuters Web of Science Article | Citations
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Created: Sun, 20 Jun 2010, 00:07:57 EST