An in vitro study of the antimicrobial activity of some endodontic medicaments against Enteroccus faecalis biofilms

Athanassiadis, B., Abbott, P. V., George, N. and Walsh, L. J (2010) An in vitro study of the antimicrobial activity of some endodontic medicaments against Enteroccus faecalis biofilms. Australian Dental Journal, 55 2: 150-155. doi:10.1111/j.1834-7819.2010.01222.x


Author Athanassiadis, B.
Abbott, P. V.
George, N.
Walsh, L. J
Title An in vitro study of the antimicrobial activity of some endodontic medicaments against Enteroccus faecalis biofilms
Formatted title
An in vitro study of the antimicrobial activity of some endodontic medicaments against Enteroccus faecalis biofilms
Journal name Australian Dental Journal   Check publisher's open access policy
ISSN 0045-0421
1834-7819
Publication date 2010-06
Sub-type Article (original research)
DOI 10.1111/j.1834-7819.2010.01222.x
Volume 55
Issue 2
Start page 150
End page 155
Total pages 6
Place of publication Oxford, United Kingdom
Publisher Wiley-Blackwell Publishing
Collection year 2011
Language eng
Formatted abstract
Background: The in vitro antimicrobial activity of a series of endodontic medicaments and their bases against biofilms of
Enterococcus faecalis was investigated.
Methods: The medicaments tested were Pulpdent paste, Ledermix paste, a 50:50 Ledermix and Pulpdent mixture, and a
replica of Ledermix paste. Bases included methyl cellulose with water, polyethylene glycol (PEG), and PEG with zinc oxide,
calcium chloride and the other components (inactives) that make up the Ledermix paste base. Biofilms grown on cellulose
nitrate membrane filters were exposed to the medicaments for up to 5 days. The number of surviving colony forming units
(CFU) was determined at days 1, 3 and 5. The results were expressed as a bacterial survival index (BSI) when compared to
the unexposed control.
Results: Pulpdent produced the greatest reduction of BSI, followed by the 50:50 mixture of Pulpdent and Ledermix pastes.
Ledermix paste, its replica and the individual bases showed no significant reductions in the BSI for E. faecalis.
Conclusions: Within the limitations of this laboratory study, calcium hydroxide containing preparations had greater
potential for reducing the survival of E. faecalis in a biofilm environment.
© 2010 Australian Dental Association.
Keyword Endodontics
medicaments
E. faecalis biofilms
Enterococcus-faecalis
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
School of Dentistry Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 6 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 7 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Sun, 13 Jun 2010, 00:08:51 EST