Whole-genome characterization and genotyping of global WU polyomavirus strains

Bialasiewicz, Seweryn, Rockett, Rebecca, Whiley, David W., Abed, Yacine, Allander, Tobias, Binks, Michael, Boivin, Guy, Cheng, Allen C., Chung, Ju-Young, Ferguson, Patricia E., Gilroy, Nicole M., Leach, Amanda J., Lindau, Cecilia, Rossen, John W., Sorrell, Tania C., Nissen, Michael D. and Sloots, Theo P. (2010) Whole-genome characterization and genotyping of global WU polyomavirus strains. Journal of Virology, 84 12: 6229-6234. doi:10.1128/JVI.02658-09

Author Bialasiewicz, Seweryn
Rockett, Rebecca
Whiley, David W.
Abed, Yacine
Allander, Tobias
Binks, Michael
Boivin, Guy
Cheng, Allen C.
Chung, Ju-Young
Ferguson, Patricia E.
Gilroy, Nicole M.
Leach, Amanda J.
Lindau, Cecilia
Rossen, John W.
Sorrell, Tania C.
Nissen, Michael D.
Sloots, Theo P.
Title Whole-genome characterization and genotyping of global WU polyomavirus strains
Journal name Journal of Virology   Check publisher's open access policy
ISSN 0022-538X
Publication date 2010-06-01
Sub-type Article (original research)
DOI 10.1128/JVI.02658-09
Open Access Status DOI
Volume 84
Issue 12
Start page 6229
End page 6234
Total pages 6
Place of publication Washington, DC, United States
Publisher American Society for Microbiology
Collection year 2011
Language eng
Formatted abstract
Exploration of the genetic diversity of WU polyomavirus (WUV) has been limited in terms of the specimen numbers and particularly the sizes of the genomic fragments analyzed. Using whole-genome sequencing of 48 WUV strains collected in four continents over a 5-year period and 16 publicly available whole-genome sequences, we identified three main WUV clades and five subtypes, provisionally termed Ia, Ib, Ic, II, IIIa, and IIIb. Overall nucleotide variation was low (0 to 1.2%). The discriminatory power of the previous VP2 fragment typing method was found to be limited, and a new, larger genotyping region within the VP2/1 interface was proposed.
Copyright © 2010, American Society for Microbiology. All Rights Reserved.
Keyword Respiratory-tract infections
KI polyomaviruses
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published under "Notes".

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2011 Collection
Clinical Medical Virology Centre Publications
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Citation counts: TR Web of Science Citation Count  Cited 7 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 8 times in Scopus Article | Citations
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Created: Sun, 30 May 2010, 00:02:26 EST