Language outcomes following treatment for acute lymphoblastic leukaemia with CNS chemotherapy: A two-year follow-up study

Lewis, Fiona M., Murdoch, Bruce E., Barwood, Caroline, Docking, Kimberley M. and Gellatly, Amanda (2010) Language outcomes following treatment for acute lymphoblastic leukaemia with CNS chemotherapy: A two-year follow-up study. Asia Pacific Journal of Speech, Language, and Hearing, 13 1: 51-60. doi:10.1179/136132810805335182

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Author Lewis, Fiona M.
Murdoch, Bruce E.
Barwood, Caroline
Docking, Kimberley M.
Gellatly, Amanda
Title Language outcomes following treatment for acute lymphoblastic leukaemia with CNS chemotherapy: A two-year follow-up study
Journal name Asia Pacific Journal of Speech, Language, and Hearing   Check publisher's open access policy
ISSN 1361-3286
Publication date 2010
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1179/136132810805335182
Open Access Status
Volume 13
Issue 1
Start page 51
End page 60
Total pages 10
Place of publication London, United Kingdom
Publisher Whurr Publishers
Collection year 2011
Language eng
Abstract Using cross-sectional and longitudinal approaches, the current research investigated the language skills of two boys following CNS-targeted chemotherapy- only treatment for acute lymphoblastic leukaemia. A single case-multiple comparison study of each boy’s general language skills, as assessed by the Clinical Evaluation of Language Fundamentals-Fourth Edition, the Peabody Picture Vocabulary Test-Third Edition Form A, and the Hundred Pictures Naming Test, and each boy’s high level language skills as assessed by the Test of Language Competence-Expanded Edition, and the Test of Problem Solving-Elementary, Revised or the Test of Problem Solving- 3 was undertaken. Additionally, using test norms only for comparison, the boys’ language skills were assessed three times over a two-year period. The findings suggest that the language skills of both boys were generally within one standard deviation of their respective control group’s mean, although one boy was experiencing moderate difficulty with high-level language tasks. Between assessment 2 and 3, the receptive language skills of both boys declined, and competence with high level language tasks declined considerably for one boy and slightly for the other. The results suggest that language skills require monitoring following CNS chemotherapy. Copyright © 2010 Plural Publishing, Inc.
Keyword Acute lymphoblastic leukaemia
CNS-directed chemotherapy
Late effects
Language outcomes
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: Official 2011 Collection
 
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Created: Fri, 21 May 2010, 13:13:50 EST by Dr Fiona Lewis on behalf of School of Health & Rehabilitation Sciences