Language skills following risk-adapted treatment for medulloblastoma

Lewis, Fiona and Murdoch, Bruce (2010) Language skills following risk-adapted treatment for medulloblastoma. Developmental Neurorehabilitation, 13 3: 217-224. doi:10.3109/17518421003733856

Author Lewis, Fiona
Murdoch, Bruce
Title Language skills following risk-adapted treatment for medulloblastoma
Journal name Developmental Neurorehabilitation   Check publisher's open access policy
ISSN 1751-8423
Publication date 2010-06
Sub-type Article (original research)
DOI 10.3109/17518421003733856
Volume 13
Issue 3
Start page 217
End page 224
Total pages 8
Place of publication London, U.K.
Publisher Informa Healthcare
Collection year 2011
Language eng
Subject 110321 Rehabilitation and Therapy (excl. Physiotherapy)
111208 Radiation Therapy
111403 Paediatrics
Formatted abstract
Abstract Objective: Recent research findings suggested that children treated for medulloblastoma (MB) may experience undiagnosed language difficulties following treatment. The aim of this report was to investigate language skills in an adolescent following treatment for MB.

Methods: This single case study profiles the language skills of GCG, a female aged 14;1 years, who was treated with risk-adapted cranial radiation therapy (CRT) for MB 4 years prior to language assessment.

Results: Difficulties recalling verbal information of increasing length and complexity and reduced competence with language requiring critical thinking and complex cognitive processing were identified.

Conclusion: The findings suggest that prospective language assessment and monitoring should routinely be undertaken in children following treatment for MB, even when less-intense treatments are delivered to reduce adverse neurocognitive outcomes, due to the vulnerability of the developing brain to CRT.
© 2010 Informa UK Ltd.

Keyword Medulloblastoma
Risk-adapted cranial radiation treatment
Language outcomes
Language intervention
Vulnerability model
Q-Index Code CX
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes This is a case report

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
ERA White List Items
School of Health and Rehabilitation Sciences Publications
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Citation counts: TR Web of Science Citation Count  Cited 2 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 3 times in Scopus Article | Citations
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Created: Fri, 21 May 2010, 12:59:34 EST by Belinda Weaver on behalf of School of Health & Rehabilitation Sciences