Encapsulating peritoneal sclerosis: Incidence, predictors, and outcomes

Johnson, DW, Cho, Y, Livingston, BER, Hawley, CM, McDonald, SP, Brown, FG, Rosman, JB, Bannister, KM and Wiggins, KJ (2010) Encapsulating peritoneal sclerosis: Incidence, predictors, and outcomes. Kidney International, 77 10: 904-912. doi:10.1038/ki.2010.16


Author Johnson, DW
Cho, Y
Livingston, BER
Hawley, CM
McDonald, SP
Brown, FG
Rosman, JB
Bannister, KM
Wiggins, KJ
Title Encapsulating peritoneal sclerosis: Incidence, predictors, and outcomes
Journal name Kidney International   Check publisher's open access policy
ISSN 0085-2538
1523-1755
Publication date 2010-05
Sub-type Article (original research)
DOI 10.1038/ki.2010.16
Volume 77
Issue 10
Start page 904
End page 912
Total pages 9
Place of publication London, United Kingdom
Publisher Nature Publishing Group
Collection year 2011
Language eng
Formatted abstract
Encapsulating peritoneal sclerosis is a complication of peritoneal dialysis characterized by persistent, intermittent, or recurrent adhesive bowel obstruction. Here we examined the incidence, predictors, and outcomes of encapsulating peritoneal sclerosis (peritoneal fibrosis) by multivariate logistic regression in incident peritoneal dialysis patients in Australia and New Zealand. Matched case-control analysis compared the survival of patients with controls equivalent for age, gender, diabetes, and time on peritoneal dialysis. Of 7618 patients measured over a 13-year period, encapsulating peritoneal sclerosis was diagnosed in 33, giving an incidence rate of 1.8/1000 patient-years. The respective cumulative incidences of peritoneal sclerosis at 3, 5, and 8 years were 0.3, 0.8, and 3.9%. This condition was independently predicted by younger age and the duration of peritoneal dialysis, but not the rate of peritonitis. Twenty-six patients were diagnosed while still on peritoneal dialysis. Median survival following diagnosis was 4 years and not statistically different from that of 132 matched controls. Of the 18 patients who died, only 7 were attributed directly to peritoneal sclerosis. Our study shows that encapsulating peritoneal sclerosis is a rare condition, predicted by younger age and the duration of peritoneal dialysis. The risk of death is relatively low and not appreciably different from that of competing risks for mortality in matched dialysis control patients.
© 2010 International Society of Nephrology.
Keyword Encapsulating peritoneal sclerosis
Peritoneal dialysis
Peritonitis
Predictors
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Faculty of Health and Behavioural Sciences -- Publications
Official 2011 Collection
School of Medicine Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 64 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 70 times in Scopus Article | Citations
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Created: Sun, 16 May 2010, 00:03:06 EST